Pain Drug - Positive Results From A Meta-Analysis Of Phase II And Phase III Data Generated With Morphine-6-glucuronide (M6G)

The biopharmaceutical company PAION AG (ISIN DE000A0B65S3; Frankfurt Stock Exchange, Prime Standard: PA8, London AIM: PAI) today announces positive results from a meta-analysis of Phase II and Phase III data generated with morphine-6-glucuronide (M6G). According to PAION, applying the findings should improve the probability of success for the development program and will facilitate the planning of future studies. Accordingly, PAION is now re-launching the partnering process for M6G.

In spring 2007, a Phase III... read more

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A new weapon in the fight against obesity and diabetes

A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues.

The new chemical entity was developed by Sirtris, a a GSK company, and the research study was led by EPFL professor Johan Auwerx, MD, says EurekAlert! release.

Reducing calorie consumption by about 20% has... read more

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Red wine pills to fight obesity, diabetes

While testing the compound, called SRT1720, researchers found that it protected mice from weight-gain and insulin disorders – even when they ate a high-fat diet.

They also found that the drug appears to increase energy levels when exercising.

It targets a protein, which is also affected by resveratrol, a chemical in the skins of red grapes that’s believed to combat ageing and help prevent heart disease and cancer.

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Diabetes, Hypertension Hasten Death in Alzheimer's Patients

11/3/2008 12:00:00 AM
MONDAY, Nov. 3 (HealthDay News) -- Having diabetes or high blood pressure may hasten the death of people with Alzheimer's disease, new research suggests.

According to the study, published in the Nov. 4 issue of Neurology, Alzheimer's patients with diabetes were twice as likely to die sooner than those with the dementia condition but no diabetes. Those with

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ConjuChem Provides Development Update

ConjuChem Biotechnologies Inc. (CA:CJB: news, chart, profile) announced today that dosing is complete for its Phase II clinical trial of PC-DAC(TM):Exendin-4. This Phase II trial was a randomized, double-blind, placebo-controlled, multiple dose study that evaluated the efficacy and safety of three months of weekly injections of PC-DAC(TM):Exendin-4 in patients with Type 2 diabetes not adequately controlled by metformin monotherapy. The trial enrolled approximately 120 evaluable patients randomized to one of three parallel treatment groups: a... read more

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Study: Florida near top in diabetes cases

The rate of new cases of diagnosed diabetes rose by more than 90 percent among adults over the last 10 years — and Florida was listed as one of the states with the highest age-adjusted incidence, according to a Centers for Disease Control and Prevention study.

The data showed that the incidence of new cases of diagnosed diabetes has increased from 4.8 per 1,000 people during 1995-1997 to 9.1 per 1,000 in 2005-2007 in 33... read more

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Opportunities to Highlight Type 1 Diabetes in November

-- Diabetes Awareness Month, in November, and World Diabetes Day (Nov. 14)
present outstanding opportunities to educate the public about type 1
diabetes screening and promising research taking place at medical
centers throughout the country.

-- The theme for this year's World Diabetes Day--Diabetes in Children
and Adolescents--is an especially appropriate focus given the increased
incidence of type 1 diabetes among children, particularly... read more

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Many more children on medication, study says

Hundreds of thousands more children are taking medications for chronic diseases, with a huge spike over a four-year period in the number given drugs to treat conditions once seen primarily in adults and now linked to what has become an epidemic of childhood obesity.

In a study appearing today in the journal Pediatrics, researchers saw surges in the number of U.S. children taking prescription medicines for diabetes and asthma, with smaller increases in those taking... read more

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Surgery May Be 'Magic Cure' For Diabetes

BOSTON -- Twenty-four million Americans live with type 2 diabetes, but doctors are increasingly convinced that some diabetics may soon be able to have one relatively safe operation and, within hours, not be diabetic anymore.

While millions of Americans have diabetes, 57 million more are at risk. According to estimates by the American Diabetes Association and the Centers for Disease Control and Prevention, medical care for diabetics eats up $174 billion per year, or as... read more

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Energy dense diet ups diabetes risk

The rate of diabetes has doubled in the past decade, according to a report released Thursday by the Centers for Disease Control and Prevention or CDC.

Energy dense diet has been linked in early studies to obesity which has in turn been associated with increased risk of type 2 diabetes. And the editorials for the CDC report said the increased diabetes prevalence has something to do with obesity, which is also on the rise... read more

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