Sickly Gums During Pregnancy May Invite Diabetes

Pregnant women with gum disease beware: You’re at risk of developing gestational diabetes. The condition develops during pregnancy and usually ebbs after the baby is born, but it can increase your chances of developing type 2 diabetes later on. According to one study, pregnant women who developed gestational diabetes had high levels of gum disease-causing bacteria and inflammation. Researchers speculate that gum disease may impair blood sugar control, leading to the development of diabetes. Published... read more

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SGLT2 Inhibitors a Promising New Therapy for Type II Diabetes

RESEARCH TRIANGLE PARK, NC, Dec 12, 2008 (MARKET WIRE via COMTEX) -- A new drug class is poised to make a splash in the diabetes market, according to a new report, "Diabetes Market Forecast to 2013" ( http://www.cuttingedgeinfo.com/Diabetes/ index.htm#body), published by Cutting Edge Information. SGLT2 Inhibitors, which block the reabsorption of glucose in the kidneys, have had positive clinical results and have attracted the attention of top pharmaceutical companies. While no SGLT2 inhibitor is currently... read more

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Exciting New Insulin Technology: Smart Insulin

The article describes a new technology being developed called "Smart Insulin," which is an insulin that responds to glucose.

The new insulin "senses" high glucose levels and automatically dispenses insulin on demand. As glucose levels drop off, the drug stabilizes, trapping insulin until the next glucose spike.

The drug will be in clinical trials within the next 2 years - seems very promising to me!!!

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Overweight Siblings of Children With Type 2 Diabetes Likely to Have Abnormal Blood Sugar Levels

PHILADELPHIA, Dec 09, 2008 /PRNewswire-USNewswire via COMTEX/ -- Overweight siblings of children with type 2 diabetes are four times more likely to have abnormal glucose levels compared to other overweight children. Because abnormal glucose levels may indicate risk for diabetes or diabetes itself, these children could benefit from screening tests and diabetes prevention education.
Researchers from The Children's Hospital of Philadelphia published their findings today in the online edition of the Journal of Pediatrics.... read more

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Of Dreams and Diabetes

Is there a link between sleep and type 2 diabetes? That's one implication of a new study, which has found that variants in a gene that helps regulate the body's daily rhythms increase the chance of developing the disease. The find, reported online yesterday in three papers in Nature Genetics, may suggest new ways to treat or prevent the ever more common disorder.
The body's internal clock--or circadian rhythm--is kept accurate by a hormone... read more

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Bad sleepers 'at diabetes risk'

People who sleep badly may be at greater risk from developing diabetes due to a mutant gene affecting their body clock, scientists said.

The mutation not only changes the way that the hormone melatonin is controlled but also disturbs the levels of insulin - the hormone that controls blood sugar, researchers believe.

They say that the effect of the mutant strain is so significant that people who carry it have about a 20% higher chance... read more

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Obesity and Diabetes: Obesity hampers the Treatment of Obesity!

People do not realize that obesity is becoming major reason behind many fatal diseases. Diabetes is one of these diseases. Obesity and diabetes both are common problems in youth as well as in old age. People are eating more and eating unhealthy and it is leading us to diabetes.

Research has shown that obesity and diabetes are inter-related. Lifestyle is a major contributing risk factor for both these conditions. Sedentary lifestyles, high fat diet,... read more

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New proteins hold clues to cure for diabetes, obesity

Toronto (IANS): A Canadian biochemist, along with his American colleagues, has discovered new proteins that work as ``master regulators'' in production of fat in the body.

Gaining control of these proteins could spell the end of diabetes and obesity epidemic in the world, said Alberta University biochemist Dave Brindley in a statement Thursday.

Called lipins, these newly discovered proteins control fat production in the mammal body, he said. In all, there are four... read more

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New Screening Tool To Identify Patients With Prediabetes

ScienceDaily (Dec. 5, 2008) — A third of Americans with diabetes do not know that they have it, and many more who have prediabetic conditions are unaware that they are at risk. A University of Missouri researcher has created a clinical tool to identify those at highest risk for having undetected hyperglycemia, impaired fasting glucose (IFG) and undiagnosed diabetes.

If these conditions are identified early, patients may benefit from preventative strategies that can minimize progression... read more

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ConjuChem's PC-DAC(TM):Exendin-4 Lowers Glucose and Weight in Phase II Diabetes Trials

ConjuChem Biotechnologies, Inc. (TSX:CJB) announced preliminary results today showing that its Type 2 diabetes product, PC-DAC(TM):Exendin-4, achieved statistically significant reductions in HbA1c and weight in its two Phase II clinical trials.

Commenting on the clinical results, Mark Perrin, President and CEO stated, "We are extremely pleased with these results which have met our clinical objectives. Achieving a 1.4% reduction in HbA1c and a weight reduction up to 2 kg with minimal side effects presents... read more

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