New Target For Obesity-Related Insulin Resistance, Type 2 Diabetes

Building on mounting evidence that implicates infection-fighting cells found in obese fat tissue in the growing problem of insulin resistance and Type 2 diabetes, researchers at the University of California, San Diego, School of Medicine have identified a particular subset of cells that are linked to obesity-associated insulin resistance, and that offer a promising new target for the treatment of diabetes. They showed that depletion of these cells, called CD11c-positive, in obese mice resulted in... read more

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U of L to conduct diabetes research

The University of Louisville has received $11.6 million from the National Institutes of Health to research how diabetes causes heart disease and how to prevent that from happening.
The university will establish a Center of Excellence in Diabetes and Obesity Research with the five-year grant, using the money to hire researchers, buy equipment and renovate part of a research building.

The agency awarded a similar grant yesterday to the University of Kentucky -- $10.53... read more

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The Truth About 7 Common Food Additives

How safe are the ingredients in your food?
By Martin F. Downs
WebMD FeatureReviewed by Louise Chang, MDIf, like many Americans, you stock your pantry with processed foods, you may worry about how safe food additives really are.

Over the years, the safety of many food additives, from food dyes to trans fats, has come into question. A scare over a food additive may linger in our minds long after researchers find that... read more

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Fighting Obesity, Hypertension, Diabetes And Other Metabolic Diseases By Computer

A new computational approach developed by computer scientists Tomer Shlomi, Moran Cabili and Prof. Eytan Ruppin from the Blavatnik School of Computer Science at Tel Aviv University may help science gain a clearer overall picture of the metabolic processes in our different tissues. Their model could be potentially used in the future to refine the diagnosis of various metabolic-related disorders, aid in treatment and develop new drugs. The results of their research were recently reported... read more

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Scientists From Granada Find A Potential Treatment To Prevent Diabetes And Obesity

A molecule called interleukin-6 has opened new doors for the creation of new drugs against obesity and diabetes. These are the conclusions of an international project which has had the participation of researchers from Vitagenes, a company which forms part of the Campus program promoted by the University of Granada (UGR) and situated in the Technological Park of Health Sciences (PTS).

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Potential Treatment To Prevent Diabetes And Obesity Using Interleukin-6

ScienceDaily (Oct. 17, 2008) — A molecule called interleukin-6 has opened new doors for the creation of new drugs against obesity and diabetes.

This is the conclusion of an international project which has had the participation of researchers from Vitagenes, a company which forms part of the Campus program promoted by the University of Granada (UGR) and situated in the Technological Park of Health Sciences (PTS).

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Calorie overload sends the brain haywire: study

Lay explanation of an article published in the technical journal _Cell_. The study, centered on mice, suggests that the act of overeating may in itself cause inflammation, inappropriately trigger the immune system, and interrupt the insulin/leptin cycle, resulting in many of the disorders that are associated with obesity.

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Early Onset of Diabetes Means Riskier Middle Age

Whether diagnosed in infancy, adolescence or adulthood, type 2 diabetes is always a serious and potentially life-threatening condition if improperly managed. However, a troubling study shed light on the particular risks that will face early-onset diabetics when they reach middle age. Published in the Journal of the American Medical Association, the study estimated that those who develop type 2 diabetes before the age of 20 face a significantly higher risk of a range of ailments... read more

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Gastric stimulator induces weight loss in diabetics

Gastric electrical stimulation using the Tantalus system (MetaCure Ltd) of implantable electrodes has been studied with an eye towards improving glucose control and inducing weight loss in obese patients with type 2 diabetes.

The Tantalus system is a device that induces stomach contractility and consists of three pairs of bipolar electrodes connected to an implantable pulse generator. The device detects food intake and pulses to induce early satiety.

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Vaccination against GIP for the Treatment of Obesity

In the effort to avert the development of diabetes, hypertension, and other obesity-linked conditions, investigators are developing a vaccination based on the premise that inhibiting gastric inhibitory peptide receptors will protect people from diet-induced obesity.

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