Lilly Announces Launch of Color Differentiation System for Humalog(R) and Humulin(R) U-100 Insulin Products in the United States

INDIANAPOLIS, Oct. 27 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY) today announced the introduction of a color differentiation system for U-100 insulin products marketed in the United States, including vials, pens and individual packaging for Humalog(R) (insulin lispro injection [rDNA origin]) and Humulin(R) (regular insulin human injection, USP [rDNA origin)]).

The Lilly color differentiation system - also used for Humalog and Humulin formulations marketed in Europe - follows the introduction of bar coding of... read more

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South Africa: Suppository Insulin Pill to Be Tested in Country

Israeli biotechnology company Oramed Pharmaceuticals plans to test the safety of its suppository insulin pill on diabetics in SA.

The trial, which will be conducted by local clinical research organisation OnQ Consulting, highlights international drug developers' confidence in the local industry.

"The level of medical expertise is high in SA, and the pricing is very competitive," Oramed CEO Nadav Kidron said.

With a growing number of diabetics worldwide, pharmaceutical companies are hunting for new and... read more

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Eyeball Your Insulin

If you’re an insulin-injecting diabetic, you should make a habit of inspecting your insulin vial every time you load a syringe. Watch for changes in the insulin’s appearance, such as discoloration, cloudiness or crystallization in the liquid. If you notice any such changes, discard the vial. Keep in mind that other changes are not as easily visible, so stay alert for any indication that your insulin may not be working as well, such as aberrations... read more

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Oramed Pharmaceuticals Launches Phase 1A Trials Of Its Insulin Suppository

Oramed Pharmaceuticals, Inc. (OTCBB: ORMP.OB), a developer of alternative drug delivery systems, announced today that it has received approval from the South Africa Medicines Control Council (MCC) to begin conducting Phase 1A trials on eight healthy human volunteers for ORMD 0802, the company's newly developed insulin suppository.

Oramed's Phase 1A trials on its insulin suppository mark an important step in the history of insulin delivery as it will provide a painless option for diabetics... read more

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Treatment for Type 2 Diabetes Updated

Diabetes Care and Diabetologica recently announced new protocols for treatng newly-diagnosed Type 2 Diabetes.

Upon initial diagnosis, lifestyle changes and metformin should be prescribed. If no improvement shows in three months, preferred treatment is to add either a sulfonylurea or basal insulin should be added into the mix. Pioglitazone, or a GLP-1 agonist, is a second (but less-well studied) option.

If there is no change within three months, then basal insulin should be started... read more

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Calorie overload sends the brain haywire: study

Lay explanation of an article published in the technical journal _Cell_. The study, centered on mice, suggests that the act of overeating may in itself cause inflammation, inappropriately trigger the immune system, and interrupt the insulin/leptin cycle, resulting in many of the disorders that are associated with obesity.

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10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

Over 4000 UK patients with diabetes were randomly assigned to diet-only, sulfonylurea and insulin, or metformin therapy and followed for 10 years. One year after the study ended, there were no differences in A1c; however, the patients who had been treated with drugs had lower risk of diabetes-related complications and diabetes-related deaths.

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Analogue or human insulins OK for type 2 diabetes

No functional difference exists between the efficacy of analog insulins and natural insulins. However, better results are found with premixed insulins than with long-acting insulins, as they better simulate the body's natural insulin responses.

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Insulin and weight gain: Keep the pounds off

Insulin and weight gain often go hand in hand. But if you need insulin therapy, you're not necessarily doomed to gain unwanted weight. Start by understanding how insulin therapy works. Then consider steps you can take to minimize — or avoid — weight gain while you're taking insulin.

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Premixed Insulin May Offer Better Blood Sugar Control

Premixed insulin, which combines short-and long-acting versions of the hormone, results in better blood-sugar control as compared with long-acting insulin alone or oral medications, a new study finds.

But it's not clear that this tighter glycemic control translates into fewer complications and a lower mortality rate among people suffering from type 2 diabetes, researchers add.

And two types of premixed insulin - premixed human insulin and premixed insulin analogues (genetically engineered human insulin) - appeared... read more

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