Like "Marty: Sounds as if you have a difficult life right now BUT you have come to right place for motivation. I would be having one heck of a "pity party" with all of your diagnoses. If I were you, I would attempt to tackle one thing at a time (of course, trying to watch everything at all times). You must take the methotrexate for the arthritis so watch your BS closely and record eating habits. If you are eating every 2-3 hours, it is really hard to be hungry enough to over eat. You can only deal with one day at a time. The doctor can always give you something for depression and you can report the "baby steps" to him on a regular basis. Try to think of the positive things you can do for yourself and always remember, you are a very special person. Good luck!"