Like "I moved to Missouri july of 2008 and since then I 've lost 50 pounds as of January 2009. But since then I've gained back 10 pounds. I think it's the Actos that my doctor just put me on in december 2008. I am very depressed about it cuz I am considered obese and I need to lose alot of weight. My self-esteem is very low and I hate that I am overweight! It is very hard for me to exercise cuz I have a hard time walking cuz of arthritis in my knees and I broke my left knee in January of 2008 and since then I have alot of pain especially when I walk! Amy"