Like "Actually what you are saying is not entirely true about medication. Metformin can create a problem if you take it and then not eat and be active. What she should be asking the doctor is if she can take it later in the day. She should also talk to the pharmacist about the medication who is in so many cases more informed on the medication than the doctor. For example, I asked the pharmacist about what to do if I forgot to take my met at night. She said you can take it in the morning first thing then take the next dose that night. I have a question for you. What do you do when the medication is for once a day, or three times a day? Do you ask your doctor what time should you take it or do you determine the time to take it? Nothing is written in stone therefore it can be changed. "