Like "Metformin (as mentioned below) is definitely associated with what you are finding. My thoughts are, you should discuss with your Dr about taking a second medication that works on a different part of your diabetes. You get 80% of the power of a drug from half its maximum dose. Therefore going to 2000mg of metformin (which by the way is 500mg off the maximum), is not going to give you much extra benefit and has increased the side effect profile of it way to much. Thats my thoughts, bottom line, talk to your Dr."