Like "There is a medicine called Actos that works the same way as Avandia, just a different manufacturer. I'd suggest calling your doctor's office and asking if that would be a suitable alternative for you. Here's a link to their website: Also, if this doesn't work out, going on insulin isn't as bad as you fear. I am very needle phobic and, using an insulin pen, the shots are not very bad at all. Going with the shortest pen needle that will work for you is the key to comfort Now I am on a pump and (naturally) chose the OmniPod as it inserts itself automatically-no need to see any needles so it works for me! "