Brand Names: Byetta, Bydureon

Exenatide is used along with diet and exercise to treat type 2 diabetes. Exenatide is in a class of medications called incretin mimetics. It works by stimulating the pancreas to secrete insulin when blood sugar levels are high. Exenatide also slows the emptying of the stomach and causes a decrease in appetite.

1. Nausea 2. Vomiting 3. Diarrhea

Community Rating: 4.2

(4 Reviews)
Rate and Review

Exenatide Reviews

Bydureon Experience

Pros: Once a week injection is great! I'm working towards getting off all insuin and everytime I cut back, Bydureon handles it. It controls my bg very well, even better than Victoza did.

Cons: The needle is huge compared to what I used for my insulin injections. The injector pen is also quite large and I'm not sure how to dispose of it correctly. Mixing seems to be a problem for some, but so far I haven't had any problems with it.

Overall: I am seven weeks into Bydureon and find that I'm liking it more and more. I was on Victoza for 4 mos until my ins made it non-formulary and my cost went up. One of the suggested substitutions was Bydureon. I haven't had any of the side effects that others seem to have struggled with. Not sure if this is because Victoza is a similar drug and I already went though some with it or because my body seems to like Bydureon better. My fbg is under 100 most mornings and daytime nos are very good, Bedtimes also under 100. Haven't had any weight loss from either med, so I guess that's just not happening for me. The first 2 weeks were a roller coaster ride as far as my bg was concerned. My bg would go up after a meal and stay there. I had to up the insulin to 15 units at night. By the third week, Bydureon started to "take root" and now I'm back to 6 units, soon to be 3. I hope this continues to work for me for a long time. BTY, diet is still a key factor in using this drug. It does have its limits and you cannot expect it to do all the work.

By suecsdy
A great med, but side effects not worth it for me.

Pros: It got my numbers down, though not as good as with Victoza.

Cons: Side effects were the same as with Victoza. Having to mix the medication myself seems a bit old-fashioned. The needle is too large. It's meant to be taken once a week, which for me is more of a con than a pro.

Overall: I didn't really like the thought of having to try to remember to take it.

By Anonymous
My Byetta and me

Pros: Kept my blood sugars even. Used for 6 years. Lost weight and I felt really good.

Cons: Occasionally had nausea and vomiting.

Overall: Though hesitant about shots, this was a good choice for me, until it no longer was bringing my sugars down. In the 6th yr. on Byetta, I noticed my eyes crossed twice and I had continuous dull pain right behind both eyes. When I went off it, the pain disappeared almost immediately. Also my eyes never crossed since I have been off.

By Rose67

Pros: Stops the high and low fluctuations in my glucose levels.

Cons: eating correctly and maintaining a 6.0 A1C.

Overall: Very Good

By SweetCameleon