How long does Actos stay in my system? I have been on Actos 45 for 5 years A1c has been 6.1 for some years. Three weeks ago I ran out of the med, and it took 2 weeks to get new order. I was going to get something from my dr. in the meantime but decided to wait to see what would happen. Well my BS morning reading has been stable at around 100 each morning. It has been 3 weeks now and my BS is still good, I am wondering if I can/should continue to wait until my next A1C test. Thanks

Dr. David Erani


By now, all of the medication has been cleared from your body. It is good that your blood glucose levels in the morning are not elevated. If they are higher later in the day, your next A1C could be higher than you expect. If your blood glucose levels are in a healthy range throughout the day, it may be that you do not need the medication. Of course you should discuss this with your doctor. Another factor to consider is the possible link between Actos and bladder cancer. We do not know that Actos causes bladder cancer, but studies have shown that bladder cancer is more common in people taking Actos. In these studies, the risk seemed to be related to the cumulative dose of Actos. A higher dose for a longer time was associated with a higher risk. With this in mind, if you decide to go back to taking Actos, you may consider taking a lower dose.

October 8, 2012 at 10:30 pm