I was diagnosed with diabetes type 2 about five months ago and put on 2000 mg of Metformin. I am 5'2" and weighed 162 pounds. I was put on a low carbohydrate, low fat diet and have since lost 30 pounds. I now eat 30 grams of carbohydrates/three times a day. I have also quit smoking, but still use nicotine lozenges (2 mg). My fasting blood glucose is still at least around 100 and is still pretty high two hours after eating a small meal. Would Remeron be keeping my blood glucose higher?

Amy Campbell


Congratulations on losing weight and stopping smoking! Remeron (mirtazapine) is a medicine used to treat depression. Increased blood glucose is a possible side effect of Remeron. Blood glucose goals for most people with diabetes are 70 to 130 mg/dl fasting and before meals, less than 180 mg/dl two hours after a meal, and 90 to 150 mg/dl before bed. Your fasting glucose seems to be within target range, although you did not mention what your post-meal glucose readings have been. While it’s possible that Remeron may be raising your blood glucose, you may, in fact, need a higher dose of metformin and/or another diabetes medicine due to the progression of your diabetes (which is perfectly normal). I’d suggest that you talk with your healthcare provider about all of your medications and find out the best treatment approach for you.