I have type 2 diabetes. Are all cells in my body insulin resistant or just muscle tissue? The brain in particular burns 1/3 of a person's energy reserves mostly in the form of glucose. It concerns me that brain cells may become insulin resistant. Furthermore, if I exercise and build new muscle mass, are the new cells insulin resistant, too?

Patty Bonsignore


When you have type 2 diabetes, all the cells in your body are resistant to insulin, including the cells in your brain. Whatever, you can do to reduce insulin resistance will help all the cells in your body including your brain cells. One way you can reduce insulin resistance, if you are able, is to increase your aerobic activity to at least 150 minutes per week. (Always check with your healthcare provider if you are starting an exercise program.) Another way you can reduce insulin resistance is to eat a lower-fat diet, because a high-fat diet increases insulin resistance. Certain medications can also help lower insulin resistance, including metformin, pioglitazone and taking insulin by injection. When you increase your muscle mass, all the muscle cells in your body will have less insulin resistance, but if you have diabetes, the insulin resistance does not completely go away.

March 12, 2012 at 9:18 pm