I have read that antidepressants can raise blood sugar. My doc only shrugged when I asked. I would like a more clear answer if you have it.

Dr. David Erani


Your question is a good one; the answer is somewhat complicated. Some antidepressant medications have been found to be associated with hyperglycemia. This does not mean that the medications caused the hyperglycemia. Some antidepressants have been found to be associated with weight gain. One possible explanation for this is that relief from depression may lead to improved appetite . Other medications, such as some of the newer anti-psychotic medications are more clearly associated with weight gain and hyperglycemia. The bottom line question is whether the benefit of the drug outweighs the risk. Depression is bad for many reasons. One reason is that it makes it more difficult to manage your diabetes. If a medication is helping someone by relieving their depression, having to work a little harder to control their blood glucose may be a small price to pay. If it seems that the medication is having a significant negative effect on weight or blood glucose, I would discuss this with your doctor who prescribed the medication to see if there are alternatives which may be less disruptive of your glycemic control.

January 28, 2014 at 4:16 pm