Many type 2 diabetics use multiple drugs to control their blood sugar levels, but don’t know what combination of drugs works best. GRADE, Glycemia Reduction Approaches in Diabetes, is conducting a study to help find the answers.

How does the study work?

Sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, GRADE is asking type 2 diabetics to participate in their study to figure out what medication best pairs with metformin to control diabetes. During the study, all participants will take metformin and will be randomly assigned one of four other diabetes medications. Participants in the study are asked to make four doctor visits at the beginning of their involvement and following that only four visits a year for care and testing.

Those participating in the study will receive diabetes medications and supplies, and diabetes care visits, lab tests, and education at no cost, regardless of their medical insurance. Study members are asked to continue treatment and visits for four to seven years, but are free to leave the study at anytime.

Who is eligible?

The following may qualify you to participate in GRADE’s study:
• Type 2 diabetic for less than 10 years
• Over 30 (over 20 if American Indian)
• Take metformin for your diabetes or are willing to take metformin
• Willing to take a second diabetes medication
• Willing to make four office visits a year for the next four to seven years

Those who are interested and think they may qualify for GRADE’s diabetes study can visit to seek further information.

To learn more about metformin:

Metformin Versus Sulfonylurea
Metformin: Side Effects and Precautions
Two Diabetes Drugs May Be Better Than One