By Sheryl Latest Reply 2009-01-04 21:38:54 -0600
Started 2008-09-21 16:02:41 -0500

I started taking metformim 3 days ago and have noticed no change in my BG levels. I take 500mg twice daily.
Has anyone else experienced this? Should I have noticed lower numbers?
I'm pretty bummed out about this cause I thought taking this was suppose to lower your BG?!!!
I drink 1/2 glass of wine with my dinner and my numbers came down nicely when I started doing that, however I expected even more results with Metformim..
Should I expect to see lower results with this drug or not?
I take my second does at 9:00pm, should I be taking it with my meal instead?

30 replies

Paula - 14421
Paula - 14421 2009-01-04 21:38:54 -0600 Report

I know its been awhile since you posted this and I just came across it now. I took Metformin for over 2 years and my numbers would not calm down. Than the doc added gilpiside still not a whole lot of help. Now for the last two months I'm on insuline shots finally things are changing for the better

Pruin 2008-10-07 12:24:28 -0500 Report

I have had poor results with generic drugs. When I switched to Glucophage, I noticed better improvement. Also, my doctor advised using vitamin D3 to help with controlling BS. You might want to discuss this with your doctor. He can test to see if you have low D3 levels.

sparkysmom 2008-10-07 12:08:14 -0500 Report

I take 500 mg pills (1 in am 2 in PM) When first started had stomach problems after about a week they cleared up.

sbelle 2008-09-28 15:20:47 -0500 Report

I also take metforin 1000xtwice a day it takes a few days do you also take any kind of shot with it? Itake Byetta 10 x2 day also always right before my two biggest meals of the day

weezer 2008-09-28 12:33:21 -0500 Report

When I was first diagnosed with Type 2 I was prescribed Metformin (which is generic for Glucophage). It did not help me much so the 2nd opinion doctor also had me take Duetact which helped lower BG. Between my diet, no alcohol (nothing against it) and watching my carb intake I keep my sugar around 100 even after meals.

Bluebutterfly 2008-09-28 06:22:23 -0500 Report

I have been on metformin forever and a day. mY bs is usuall pretty good unless I eat something shouldn't. Give it some time. I agree with three to four weeks to get full benefit.I also take glyburide,and Januvia.

Starfire - 23364
Starfire - 23364 2008-09-28 03:06:16 -0500 Report

Hello I'm new to this site. I was told I had diabetes bach in 95 since then it has been a roll-a-coster for me I am suppose to be taking metformin 1000mg twice a day with Janumet How ever my Ins. won't pay for it because of the fact I also take 100c of lantus at night and the FDA has not approve of two meds being taken together so. here I am just on the metformin and my BG is running around 200 when I test (fasting) in the am I also have a glass of wine just before bedtime helps me sleep. I haven"t really seen any difference in a lower BG count but I'll let you know if that changes. Just remember I'm working with half my meds so there might not be a big change for me. It does take some time to get into your system. Good-Luck

Elfin 2008-09-27 22:39:50 -0500 Report

I've been on metformin for over a year 1000 mg 1 x daily. Occasionally it will cause diahrea (darn that word, I can never spell it right) but the poitive effects out weigh the bad. I find that if I take it with my evening snack, my morning BS is usually in the 80 to 112 range. I have tried wine but it had little effect for me, I do better with vinegar…doesn't really lower BS but reduces highs after meals. The only thing about vinegar though is that it may etch tooth enamel. Gosh if it isn't one thing its another :-\

beccag 2008-09-27 17:41:18 -0500 Report

Thanks Sheryl for the tip. My husband takes 500mg twice a day. And we noticed his BG level is like a seesaw (sometimes near normal level but most of the time still high). He already lost weight, watches his diet and exercises 30 minutes 5 times a week. We are still not satisfied with his BG level. He will go back to his dr next month.First, will try the small intake of red wine with dinner. I hope that it will work for him also. If not, will just forget it.
Btw, will you please tell me exactly what kind/brand of red wine you are drinking? We are not really familiar will the types. Thanks.

Sheryl 2008-09-28 05:47:50 -0500 Report

beccag, sounds like your husband is doing everything we are asked to do to control this disease…it can only be frustrating to say the least!
Is he watching those sneaky carbs? One slice of 100% whole wheat bread has approx 23 plus grams of carbs. A sandwich would be 46 grams. I have had to rethink my carbs. There are a few breads on the market that have double fiber that reduce the carbs quite a bit. Just about everything we put in our mouths has carbs and they are trying to kill us! lol
As for wine, I am not a good one to say which would be best because I am not a wine drinker. I do use a Merlot and have tried a number of them. Some so bad I can't drink it and others much more acceptable. It depends on your individual taste for wine because it sure does vary. If you would prefer the sweeter/fruitier merlot there are several which I prefer that have given me good results. I don't have a bottle right but I think I posted in my other discussion and will go look for it and post it.
Wish your husband good luck with his diabetes and hang in there, not much else you can do…

Sheryl 2008-09-28 05:53:58 -0500 Report

The wine I started with and like is called, Wild Vines Blackberry Merlot. On sale I got a 50.7 floz bottle for $6.99. It's on the sweeter side but didn't seem to effect the outcome. A half of glass of wine isn't much and the benefits are striking when it works.
Good luck and let us know how it works for you.

caspersmama 2008-09-28 06:07:20 -0500 Report

I like Sutter Home Merlot. It is $6.99 here in Tennessee. I started with that because I used to drink other Sutter Home wines but it has a nice berry taste, not to sweet.

gammi 2008-09-27 17:35:38 -0500 Report

Hi Sheryl, I take Metformin and always take it with meals. Are you taking anything else besides the Metformin?

Sheryl 2008-09-28 04:23:55 -0500 Report

No, I only take Metformin…My diagnosis is recent.
I was asked to control this with diet and exercise and did 'okay' for the most part. Found the red wine idea which helped bring my averages down. However I asked the Dr for Metformin as an added defense.
I have had no side effects from the Metformin, I take it with food. Also I am on a low dose, 500mg twice a day. Perhaps this will allow my body to adjust in the event the dose needs to be increased?

KELLY P 2008-09-27 17:16:44 -0500 Report


curt - 21856
curt - 21856 2008-09-27 13:09:24 -0500 Report

My wife takes it and it makes her sick at her stomach. Does anyone else have that experience

Starfire - 23364
Starfire - 23364 2008-09-28 03:28:11 -0500 Report

Hi Curt Is your wife taking the (met) with her meal?? Have her try taking the (met) with food even if it's a sandwhich remember whole wheat bread is better then white bread . I had the same trouble also a sour taste in my mouth. I have notice that taking it with food I don't have that trouble anymore.

Joyfaye 2008-09-28 15:48:26 -0500 Report

I started Metformin about a month ago and it helps keep my BG in line. But I do have problems with the diarrhea about once or twice a week. One night I also had vomiting.

I do not know if I can keep taking it with the D. problem. It is very debilitating and awkward at work if I have to leave a meeting to go to the bathroom.

Does it help to take it always with food? I usually do.

Anonymous 2008-09-27 11:54:57 -0500 Report

i take 1000 mgs twice daily and it helps me greatly. i have been able to come off insulin as a result. only thing is it causes diarrhea often and that is not much fun.

Anonymous 2008-09-27 11:54:57 -0500 Report

i take 1000 mgs twice daily and it helps me greatly. i have been able to come off insulin as a result. only thing is it causes diarrhea often and that is not much fun.

Anna Maynard
Anna Maynard 2008-09-27 08:16:54 -0500 Report

I take 2 pills 850 mg daily. They make me so ill sometimes … am in constant state of diarrhea and stomach cramping.

Then I will go for a couple of weeks and feel fine. The nausea is what is getting me down.

Meme55 2008-09-27 07:48:15 -0500 Report

I have been taking the metformin for several months and I had tummy aches and runs till recently. I take 1,000 mg twice a day and they say to take it 12 hours apart. I take it between 8 and 9 in the morning after my breakfast and before I go to bed probably an hour or so after dinner. I feel pretty good and I am trying to do my diet properly. I am not perfect and sometimes overeat and too fast, old habits. But I am also loosing weight slowly and walk at least 3 or 4 times a week. I am praying that it all comes together. All we can do is try.

JEB 2008-09-27 05:08:12 -0500 Report

Patience. It may take a while, or your physician may need to up the dose some. I take 850 tid.

sally - 16965
sally - 16965 2008-09-27 04:51:27 -0500 Report

i started out with another pill & between meals my sugar would go very high so i cnanged drs. he put me on 500 metform 2x a day it still didn`t do my highs any good so he uped my metformin too 2000 a day now i`m great .my sugar is around 150 sometimes a little higher. i try to not go over 200

Serreta 2008-09-24 13:12:15 -0500 Report

Hi! I also take Metformin and I also take Glyburide. I have noticed that if I take my meds to late I tend to experiance Low BG. Then I have to get up in the middle of the night to bring it back up. Maybe ou need to start taking it with your meal instead of so late at night.
Good Luck and God Bless

Connie4849 2008-09-24 17:59:10 -0500 Report

It took my body several weeks to feel the effects of metformin. Then my doctor raised my daily dose to 500mg 4 times a day. I really had a problem with that dose. My stomach was upset, I had the runs etc. etc. etc. So be careful and monitor your BG. Take it with a meal if you have a reaction to it. Because my A1c was 5.5, my doctor let me get off metformin. I'm so happy now. I control my BG with diet, and I exercise 4 times a week now. I love my Tai Chi, Qigong classes. Best wishes,

kdroberts 2008-09-22 06:19:29 -0500 Report

Metformin is a curious but fantastic drug.

Firstly, it will take a while to get fully going, 3-4 weeks is not uncommon. Secondly, you are on a fairly low dose. It's actually under the clinical therapeutic dose. Taking it with food is a good idea as it helps minimize the side effects. I think it actually says to take it with food. I take mine during a meal, some people do it before or just after.

The only thing to watch out for is your alcohol consumption. Run it past your doctor but 1 glass of wine a day isn't going to hurt (lots of people do it) however heavy drinking can cause some very serious problems. Especially if you have renal problems.

butterfly_8 2008-09-22 05:58:59 -0500 Report

What works for you may not work fo someone else.The Dr. prescribes individually.I have been taking metformin since I was diagnosed 2 1/2 yrs ago. I take 2 pills 500mg each,once a day with biggest meal. It works well. I have no complaints.

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