Avandia-The New Dangers

By Katsarecool Latest Reply 2011-04-21 18:52:20 -0500
Started 2010-06-29 07:58:23 -0500

I saw a special alert on ABCNews yesterday done by Dr. Richard Besser about this drug. Anyone else see it? I will get the web site and post as much as I can here. Some terrible statistics on the connection between this medication and an increase in heart attacks and strokes.

25 replies

edvel54 2011-04-21 18:52:20 -0500 Report

I did not see it, but I was taken off both Avandia and Actos for that reason..that it may cause heart attacks and stokes

nancysdojo3 2011-02-27 18:39:32 -0600 Report

Be careful with Avandia. I took it while doing a drug study for victoza and after a week of starting the Avandia b4 I ever started the Victoza shot I developed rapid atrial fibrilation. I truely feel like the Avandia caused this and my protime nurse said she sees alot of afib with people who were on Avandia. Of coures the Drs don't own up to it but I lived it. I'm on the victoza shots now that they have been fda approved and they are working great. Insanely expensive though.

GabbyPA 2010-07-19 06:36:08 -0500 Report

The thing is there are other options out there. I really think that we need to have our doctors understand that we want to exhaust those options before we start taking a drug that can cause just as much harm as it does good. The fact that many diabetics have heart issues is alone a reason to make sure that the drugs that are developed for us do not add to our risks.

stacey71 2010-07-18 08:34:50 -0500 Report

my daughter went to the dr.s a few weeks ago and the dr. wants her to start taking avandia but i seen the news that night i will not let her take them

ReneeIn NYC
ReneeIn NYC 2010-07-18 06:30:39 -0500 Report

I had been taking Avandia for about fifteen months. I was concerned about the side effects and when I discussed this with my doctor, she said that people with diabetes also tend to have heart problems. In April, she doubled my dose of Avandia and also gave me a referral to a Cardiologist.

On May 31st, while I was away for the weekend, my left arm went numb and I started to have chest pains. When I got home, I called a cardiologist's office and explained the situation. They gave me an appointment four weeks later. I immediately stopped taking the Avandia. My blood sugar levels aren't that much higher than when I was taking the Avandia. However, I'm scared. I haven't told my primary care doctor what happened or that I am no longer taking the Avandia. I'm doing some tests with the Cardiologist. I don't know what's next.

Katsarecool 2010-07-19 06:43:58 -0500 Report

Renee, how could your doctor brush off your concerns so easily? And then double the dose!I had a heart attack on March 14, 2006 long before getting the official diagnosis of diabetes. I would suggest that anyone experiencing symptoms of a heart attack call 911 immediately! Don't wait! Heart attacks are the leading cause of death for women.

GabbyPA 2010-07-13 20:22:23 -0500 Report

I was watching FOX News tonight and they are saying that there might have been a cover up by GSK nearly 10 years ago about studies that said there were heart related side effects with the drug. I would say there are going to be some issues with the FDA as well because they also accept funding from the drug companies AND approve the drugs...talk about a conflict of interest. What a mess.

Katsarecool 2010-07-14 19:52:26 -0500 Report

Gabby, it really is. And the people who pay for it are diabetics who have a measure of trust in the doctors who prescribe these med and the drug companies who manufacture them Corruption is everywhere it seems. And we are caught in the middle trying to life our best life.

GabbyPA 2010-07-14 20:29:23 -0500 Report

The sad thing is that it is not only diabetes medicines that cause issues. There are so many, it is very sad. No wonder we have such reservations when a doctor prescribes yet another pill...sigh

MAYS 2010-07-14 20:30:42 -0500 Report

It's the nature of business, it's all about making money.
Make enough money, cover all the lawsuits, pocket the profits.
Bring a new medication to market, start the process all over again.
(The circle of business) Here we go again !


Katsarecool 2010-07-13 12:12:31 -0500 Report

Looks like the story about Avandia is not going away any time soon. It is sad to say that there are some irresponsible drug companies that push a medication before long term studies are completed. I am not citing the manufacturer of Avandia exactly. But there have been a lot of drugs pulled because of dangerous side affects in the last ten years or so. Says more about the FDA really.

AuntieBear 2010-07-07 01:26:29 -0500 Report

I am on Avandia. I also have read about the risks. Many family members/friends harrassed me about getting off Avandia. At the time they were harassing me, I was having a lot of trouble with dizziness. So my doctor did some heart tests to rule out cardiac concerns. My heart is in great shape. There are no other signs of any of the other negative affects/effects of Avandia. My doctor keeps an eye on that stuff. He is very cautious about me because I tend to be paranoid about my diabetes. I have told my family to buzz off because I am sticking with Avandia, especially since it works wonders on controlling my numbers.

Katsarecool 2010-07-07 06:26:28 -0500 Report

I agree Auntie, you have to make your own decisions on what is best for you. Sounds like you have an attentive doctor and that is great. Good luck on passing your testing for your heart!


Nancy Ann

MAYS 2010-07-06 23:26:11 -0500 Report

This warning is from the official Avandia website:

AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart), you cannot be started on AVANDIA (see Boxed WARNING).

AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart) you cannot be started on AVANDIA. AVANDIA is also not recommended if you have heart failure with symptoms (such as shortness of breath or swelling), even if these symptoms are not severe.

AVANDIA may increase your risk of other heart problems that occur when there is reduced blood flow to the heart, such as chest pain (angina) or heart attack (myocardial infarction). This risk appeared higher in patients taking medicines called nitrates or insulin.


(Personal Note)

There is no reason why a consumer or patient cannot research the possible side effects of medication on their own behalf.
All medications have some unwanted, undesirable, harmful if not fatality causing side effects.

Do your research, it's your health and life at stake.
Take a few minutes to seek out information and answers to your questions.


ONeil 2010-07-06 22:23:54 -0500 Report

well I was taking it untill I read about it ande then I herd about on the Tv so i went and told my Dr to take me off it and he did . do to the fact that I did not want to be one of the people that is going to have the sideafates of the drug. See the studies that they did on that Drug was very short and last year a lone theire was over 300 or more that have died of this Drug. see they only tested it for only 6 month and to me that is not lone enough to keep on the shealve. I could have been wroung on the time frame in the testing but I do know that it was a very shrot time. I do agreed that if some is taking this Drug that they should be very well known of if and let them make up their mines if that is what they would like to do.
I thank you for this.

Katsarecool 2010-07-06 23:01:30 -0500 Report

I think the drug companies tend to be irresponsible in testing before releasing it for patient use. The FDA at times bow down to their incredbible pressure.

Case in point is the NSAIDs the professed to be okay. Bextra, Naproxen, Celebrex, etc. So many of them caused a lot of needless deaths. While some still on the market have helped many patients.

Another aspect is the the drug companies put a lot of pressure on doctors to prescribe medications and the doctors are not often aware of the dangers and side affects either. Doctors should be more aware of these situations and possible problems with intereactions with the other medications they prescribe.

The only answer is to educate ourselves and discuss at length the risks involved with our doctors. If we have a doctor that doesn't want us to talk about it then perhaps we should replace her/him with one that does.


Nancy Ann

GabbyPA 2010-06-29 19:43:20 -0500 Report

I also read this on www.drugs.com in their newsletter that I get. As with all medicines, even aspirin, we have to weigh out the risks and the benefits. Sometimes it's a hard scale to read.

kdroberts 2010-06-29 08:32:24 -0500 Report

This has been debated for 3 years now and so much has been said on both side of the argument that it's impossible to get to the truth. 2/3 diabetics die from heart related complications, that's a 66% chance, the chance of Avandia causing problems with the heart are still less than 1% as far as I know. So there is a risk, it's small but looks increased compared to people not taking Avandia, but the risk of uncontrolled diabetes is far greater so it's one of those things that needs to be evaluated on a case by case basis.

Katsarecool 2010-06-29 09:43:34 -0500 Report

I don't want to cause a panic or anything. I just ask that folks read the article. Seems this message is something new.

kdroberts 2010-06-29 10:44:34 -0500 Report

They are new studies but they are really saying the same things. I have been told by some people who know Dr Nissen professionally that his involvement in this may not be primarily about patient safety and he is trying to raise his profile in order to make a run for FDA commissioner. I don't know how true that is but he has a very, very high opinion of himself and his beliefs, some say an almost god like opinion.

Gilad 2010-07-06 15:38:54 -0500 Report

Here is some analysis of the numbers http://junkcharts.typepad.com/numbersruleyour...:

If you take Avandia, you have a 0.1% chance of getting better but a 2% chance of getting a heart attack. Or put differently, the chance of having the heart attack is 20 times higher than the chance of getting better. There you go, make a wise choice.

this is known as "Lies, damned lies, and statistics" http://en.wikipedia.org/wiki/Lies,_damned_lie...

GabbyPA 2010-07-06 21:56:17 -0500 Report

That is a great article on Wiki. I have never heard the quote, though I am very familiar with the concept. It is used in every poll and set of statistics known to man...no wonder we don't know what to do. Sometimes you just have to follow your gut, no explanation required.

Next Discussion: www.kingdomcare.com »