Invokana may increase foot/leg amputation risk

By onafixedincome Latest Reply 2017-06-02 21:49:30 -0500
Started 2017-05-17 00:04:30 -0500

This is NOT good news, folks. PLEASE do your research and guide your treatment accordingly!! Black box warnings are never, ever added lightly, and this may wind up being applied to the drugs as a class as more evaluations and research are done.

6 replies

WASHED OUT 2017-06-02 21:36:56 -0500 Report

Today, I visited my friend at the Hospital that I posted about around a year ago when his glucose got to low. He has now had two surgeries to try to save his foot and one to take his foot and part of his lower leg off. I am not sure that he ever took Invokana but that may be a question I need to ask him or his wife. It is so sad to see him with that stub they left him with, hopefully he will recover without have to lose even more of that limb.

GabbyPA 2017-05-17 11:49:57 -0500 Report

Just like Actos....great to use then bam with the black boxes....very sad that we get people used to using them and then they are faced with this kind of choice.

onafixedincome 2017-05-19 00:07:30 -0500 Report

Even sadder that they are rushed through approval BEFORE these things are found out. :( However, sometimes the issues don't show up even in the best studies until they are widely used. :(

GabbyPA 2017-05-22 09:32:18 -0500 Report

True, trials are just that, trials. They are not 100% conclusive, and I do understand that, but makers of these things must see some kind of red flags with all the side effects so many of the drugs have these days. It's creepy. Makes me afraid to try much that is new because of what might be coming down the road.

WASHED OUT 2017-06-02 21:49:30 -0500 Report

Exactly Gabby, they put these things out on the market before they even know the full side effects, but by then they have already harmed someone or cost them their life. They should be proven safe before they are released but that isn't the case we are faced with. I have been prescribed and taken many drugs that were later taken off the market due to harmful effects or even death. I am like you, I don't trust the doctors or the pharmaceuticals to do what is right for my health. I carry two heart stents in my body that were later recalled and taken off the market due to problems. Once they go in there is no removing them without risk to my life. I wish there was a better way for American Health providers to know they were about to cause more harm. We live in a reversed system where things have to be proven to cause harm or death before changes are made, rather than proving them safe first.

Luis65 2017-05-17 11:07:09 -0500 Report

I have been suspecting SGLT2 inhibitor class drugs since I 1st heard of them- It was the mechanism of increasing the amount of glucose excreted in urine that was a red flag for me. That just seemed wrong to me. Here's a list of current drugs in that class:
Invokana generic name: canagliflozin
Jardiance generic name: empagliflozin
Farxiga generic name: dapagliflozin