Insulin and blood sugar problems

By Ladyj01080 Latest Reply 2014-11-09 16:03:08 -0600
Started 2014-11-09 15:08:30 -0600

I was started on Humulin R U500 which is a long acting insulin. Recently my doctor took me off the U500 and put me on novolog(Short acting) and levemir(long acting). I started this on 11/6/14 and since I started it my sugars are going up. I accidentally took the u500 and levemir both long acting and my sugars leveled out normally. Anyone have issues with u100 insulin?

3 replies

Type1Lou 2014-11-09 15:18:42 -0600 Report

Because my insulin sensitivity factor is high (at 100,) I have been able to use U100 insulin effectively throughout my 38 years with diabetes. (Novolog and Lantus when I injected and now, Novolog only in my pump.) U500 is more concentrated insulin, and, as I understand it, is used by people requiring more powerful insulin because of the degree of insulin resistance they have. Humulin R stands for Humulin Regular. Regular insulin is not as fast-acting as Humalog or Novolog (which peak sharply at 60 minutes after injecting) but R has a shorter duration of action than long-acting insulins like Lantus or Levemir (20 to 24 hours duration). Regular insulin peaks 2 to 3 hours after injection and can have a duration of up to 6 hours (according to Gary Scheiner in "Think Like a Pancreas".)

Ladyj01080 2014-11-09 15:30:29 -0600 Report

Hi type1Lou: I became insulin resistant about a year and a half ago. Which is when the doctor put me on u500

Type1Lou 2014-11-09 16:03:08 -0600 Report

Have you discussed your concerns with your doctor? The key is to find the right balances and dosages that work for you individually. Are you tracking the carbs that you eat and bolusing (with Novolog) accoding to the number of carbs you are eating? We all have a different carbohydrate to insulin ratio that will work for us. Because my insulin sensitivity is 100 (highly sensitive to insulin) my ratio is 25 grams of carb to one unit of insulin (which means that for every 25 grams of carb that I eat, I need to use one unit of insulin to handle those carbs.) I would suspect that your ratio will be much lower…maybe 5 or 10 grams of carb per unit of insulin? Something to certainly discuss with your doctor.

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