By rbergman Latest Reply 2015-02-23 19:52:23 -0600
Started 2009-03-31 22:20:18 -0500

I have been on this medication since March 11th. I was put on it not for high blood pressure but to aid in kidney function for diabetics. When I first started it I was taking it at night about an hour or so before I went to bed. From the first night I found myself waking up often and seeing things that weren't there, hallucinations I call them, the room would be all one color, like red, but everything in the room was a different shade of red so it all didn't run together as just one big red blob. I would see people standing there that really weren't and even saw a 2 headed goat at the foot of the bed…this went on for about a week or so and I went and talked to the doctor about it and she said to stop taking it at night and to take it in the morning instead. So, I started doing that. All the odd activity at night stopped so I thought okay, things are better now.
About a week ago I noticed that I had this hoarse voice issue going on, having to clear my throat a lot when speaking and words being broken when I talked where my voice would just go out. No sore throat or cough just this nagging hoarseness. Then, a few days ago I noticed that my skin is extremely dry and rough, something that has never happened to me before and even though we have had some freakish weather lately and blizzards and winds, I've been through that before and it never affected my skin like this. I have also noticed my eyes feel puffy all day, like that puffiness when you first wake up or when your really tired.
I wanted to know from anyone taking this medication or that has taken it if any of this sounds familiar to you. I have talked to another person from this site that had the hoarseness and voice issues but would really like to know if any of the rest of you have had any of these experiences with Lisinopril?


29 replies

lorider70 2013-06-02 14:51:25 -0500 Report

I was on lisinopril (two a day); but it caused potassium level to rise too high. Now on one lisinopril and two carvedilol which seems to work; although the combo makes me feel a little giddy when i first take them.

jigsaw 2012-12-28 20:48:04 -0600 Report

This is really interesting! I was experiencing hoarseness and difficulty clearing my throat (mostly in the morning) for a few years. My primary care physician sent me to an ear nose and throat specialist that went down my throat via my nasal passage and discovered some minor inflammation in my larynx area. He was not very concerned about it, and did not instruct me to do anything about it. Here's is the kicker…
I was taking Metformin up until recently. I insisted for some time that it was constipating me. Three doctors doubted that Met was the cause, since it typically causes diahrea most commonly. Well, I cut the dose in half, and the constipation subsided, but my blood glucose became difficult to control. To make a long story short, I am no longer on Metformin, my constipation has subsided, and there is a bonus !! My hoarseness and difficulty clearing my throat, suddenly disappeared. I can bellow once again.
So now your probably wondering how I control my blood glucose. I am taking fast acting insulin in place of the Met. I have also been taking Lisinopril through this entire situation, and I still do. My bg is currently well controlled also, my voice is back full force, the constipation is subdued, and I'm satisfied for now.
The question is, was it a combination of the Met and Lisinopril, or just the Met? So far no problem with Lisinopril as far as I can tell.

capjoe 2012-12-28 19:09:00 -0600 Report

I lost my voice and could not hear as well as the hallucinations. I was in ICU three times from that crap, and finally a VA Doctor figured it out!

sunshine52 2009-04-14 02:04:23 -0500 Report

My nephrologist warned me when he put me on Lisinopril for the first time in February to take the protien out of my urine, that it might give me many of the side effects that you have mentioned - although, he said it is usually the generic version of Lisinopril that does it and the more expensive brand of the drug does not seem affect people in that way. If you're on the generic, try asking the pharmacist for the brand name product and see if any of the symptoms disappear. Otherwise, see your doctor again!

Blue 2009-04-13 19:59:11 -0500 Report

I am not one to pussyfoot around with meds, if it does something too weird for me, then it doesn't go into my body anymore! I have tried so many meds for different things and it's taken me awhile to find the right ones but I'm pretty intolerant of side-effects!

roger 2009-04-13 19:51:49 -0500 Report

this is what my print out lists for possible side effects
headache, drowsiness, dizziness or lightheadedness,tiredness,weakness, and cough.and see your dr if you experience fast or irregular heartbeat ,prolonged nausea, vomiting or diarrhea. hope this helped

Blue Carnation
Blue Carnation 2009-04-13 19:04:04 -0500 Report

I have not had any side effects with lisinopril, I have been on this medication since 2007, Do you think you could have an allergy to the medication.

Splender 2009-04-06 11:02:43 -0500 Report

I've been on Lisinopril for about 6 years now, and have had no reactions to it. I guess I'm one of the lucky ones. But yes I am taking it for my kidneys also—along with metropolol. Maybe your combination is not the right one for you. That is if you are one other blood pressure meds. I hope these issues get taken care off for all of you. I was told that the Lisinopril is helping me. My BS'S were very high for over 1 1|2 or more years—they started to be over 500 after I had to have my right hip replaced in 2003 and it took me until the late 2007 months. I had to be put on U-500 insulin and was on that for over a year before my sugars came down to around the 300'S. This is why my doctor put me on the Lisinopril. LOL to all of you who are having this problem. Oh yes I take mine in the morning also. Maybe that's why I've never had a problem with it. I was never told to take it at night. I wonder why? My doctor never told me when to take it so I automatically took it in the morning. TAKE CARE EVERYONE!!



DJ 2009-04-06 07:22:41 -0500 Report

I was just put on this Med for BP/Kidney Protection..and am taking it in the Evening at dinner time,as I have issues with meds and stomach the last couple nights I have noticed I start itching about an hour after taking this med,and the itching gets worse once I lie down to try and sleep(and I say try…because since starting this stuff..It takes me 2 hours to even dose off!!),between the itching and the tingling it is like "Fire ants"nibbling at me,all night. This is also present during the day,as well as the dry throat feeling you speak of. My fear now is that I may be allergic to this Med..but given my history with my Endo,and her feeling that I don't want to follow her perscribed treatment(she wants me on Janumet & Prandin, and they both make me deathly ill)…I am sure that talking to her about it will prove non-productive.I had an allergic reaction to a Med some years ago that almost cost me my life, so I am aware of the way it feels..and this is starting to feel that way to me.

rbergman 2009-04-06 10:18:45 -0500 Report

I would suggest trying to take the med in the morning with breakfast, but check with your doctor to see if moving the time won't interfere with other medications you may be taking. I don't have any issues at night now since switching it to the morning. The hoarseness and such I have during the day is still better then the affects I was experiencing when I took it at night.


DJ 2009-04-14 06:59:46 -0500 Report

Wonder of wonders my Endo actually listened to me and told me to stop taking this Med, and now 7 days later it has finally stopped making me itch like a crazy person!!She said we will look at other options once we are sure it was the I have to call her back today and see what comes next…but the Lisinopril wasn't for me. I sure hope the next one works better.
Oh, and BTW I was beginning to get some really weird dreams with it also…so, Nope this is not a med for me…but I am glad to hear that it does work for some peole here.Hugz,*DJ

midget 2009-04-05 08:24:04 -0500 Report

i've never had a problem with lisinopril, it keeps my blood pressure in order.

rbergman 2009-04-05 08:28:34 -0500 Report

Thank you but I don't take it for my blood pressure, that is fine it was given to me for aiding with kidney function, which I thought odd but turns out I'm not the only diabetic here on it for that purpose. The hoarseness is still present but no cough as of yet for me, its just more of a pain in the butt to have to clear my throat constantly in order to speak…some might say its not a bad thing that I cannot speak…lol

lipsie 2009-04-03 05:14:22 -0500 Report

I was on it it for a couple years a least and never thought nothing really, but I did have a hoarse type voice at times, never did I link the two tho hun. Sheila

jimstez 2009-04-02 21:25:24 -0500 Report

I have been taking one every evening b/4 bed but lately I have been waking up with such a dry mouth that I have changed to taking in the AM. Now I notice I am hoarse every day and wonder if that is why. I am going to ask my dr. on my next visit.

rbergman 2009-04-05 08:32:18 -0500 Report

I too had the dry mouth in the middle of the night when I would wake up, and like you, the hoarseness started after I switched to taking it in the morning. Let me know what your doctor says about it.

Momto3 2009-04-02 19:52:22 -0500 Report

Hi Robin, I have been taking Lisonipril for HBP for about a year and a half and never experienced any of these symptoms! Could they be a result of some kind of bad interaction with any other meds you may be on?

kdroberts 2009-04-01 08:15:28 -0500 Report

Well, most of that is side effects of ACE inhibitors and something you might want to talk about with your doctor. I would predict that soon you will start to get a dry cough that nothing will stop. If your doctor really thinks you need the benefit of an ACE inhibitor but you have issues with them you can try an ARB. It's a very similar class of drug but doesn't carry the side effects that you are having. Downside is they are newer and more expensive.

2009-04-01 08:37:27 -0500 Report

I switched to an ARB type blood pressure medication. I was on an ARB and they tried the Lisinopril because it was cheaper but I got the hoarseness and then a cough so they switched me back to the ARB. I was on Diovan and now I'm starting Benicar as it's a little cheaper through my insurance.