Insulin Sensitivity Factor Number

By dj7110 Latest Reply 2009-03-24 13:15:19 -0500
Started 2009-03-13 09:13:50 -0500

How do I calculate my insulin sensivity factor number? Mine is currently 22, and I strongly believe it needs to be adjusted, and don't know what equation is used to come up with the IFC number. My dr has been on me to get my sugars in better control before my surgery. And I'm totally stressed out trying to and can't figure out why other than my ISF number I use for my humalog that I was first started on might be a bit off. I've had a rough time of it last few weeks. Don't want to sound like a complainer or anything like that, but due to my circumstances it's important to get my sugars in better control.

19 replies

2009-03-17 23:05:17 -0500 Report

My sensitivity number is 40, my carb ratio is 10. These numbers were reached when I got on the pump.

In all honesty, I think it's just too much work and almost to the point of being anal to go to such extremes to figure this number out! If you don't want to feel that diabetes is controlling you, then just do the best you can!

If this has offended anyone, I do apologize.

dj7110 2009-03-18 08:39:26 -0500 Report

my carb ratio is also 10, I agree.. have enough trying to figure up with what to take.. so just giving off last weeks readings of my insulin intake, and carb intake, as well as b/s readings from now on and letting the diabetic center do the calculations for me.. a lot easier.

dj7110 2009-03-17 10:29:29 -0500 Report

actually I'm a type 2, which is why I never understood this calibration on this number and why it doesn't seem to work properly for me.. I got ahold of the diabetic center that orriginally configured my way to take my humalog to refigure it and sure enough I'm off from where I am now. My doctor upped my humalog to 55 units a day and the new number i'm using in figuring my humalog is 18. hopefully I will be having beter results now with the increases in my insulin.. I see the surgeon this week for my surgery but it won't be scheduled till after my heart stress test. So hopefully my numbers will be running a lot better by than. Thanx for all the input & help. this place is awesome. David

lipsie 2009-03-17 10:53:20 -0500 Report

David, just being nosey here…what kind of surgery are you having may I ask? Glad you got things worked out now, it looks like. Sheila

dj7110 2009-03-17 14:48:08 -0500 Report

colonoscopy.. i have been passing blood off & on for aprox a month. Had polyps removed last time aprox 3 1/2 yrs ago So have to have this done every 5 yrs. but seeing the recent problems of blood.. need to have it done again.

vgarrison 2009-03-18 00:14:38 -0500 Report


Good luck with your numbers and the surgery. I know my dad has it done every few years, there is a history of colol cancer in our family. He always says that going thru the colonoscopy is better than doing nothing and not seeing his grandkids grow up. I tend to agree with him on that one.

Blessed Be

jsd2005 2009-03-14 09:10:58 -0500 Report

Insulin sensitivity factor is generally calculated. Generally it is used for individual's on a fast acting insulin such as regular, However, health care professionals use the 1500 rule. Divide 1500 by the daily dose or requirements for insulin in units. For example if a persons total daily dose of insulin is 30 units, their insulin sensitivity factor would be 50 (1500 divided by 30). So, one unit of insulin would be estimated to lower the blood sugar by 50mg/dl.

1800 is the number used to calculate those using nova-log or humalog. It has also recently been approved for Apidra. This is done by dividing the total daily insulin requirements by 1800.

The sensitivity factor can only be used by those with type 1 diabetes. If you go to BD they have a great chart to help you calculate this factor.

Insulin resistance is a condition in which normal amounts of insulin are inadequate to produce a normal
response. Calculating your insulin factor can help you determine your insulin needs in illness etc..

I hope this helps

lipsie 2009-03-14 06:57:32 -0500 Report

I am so not into the math/number thing and don't follow fully but at least I have a idea. I don't need to know, just was wanting to understand everyone to a degree yanno. And its for Diabetics with 1 only, I just feel so awful cuz type 1's seem to have to go thru so much more then me as a type 2. Anyhow, thank you all. Good luck. Sheila

2009-03-13 19:08:21 -0500 Report

DJ, see if this helps any.

The drop in blood glucose level, measured in milligrams per deciliter (mg/dl), caused by each unit of insulin taken. Knowing their insulin sensitivity factor can help people with Type 1 diabetes to determine the dose of short-acting or rapid-acting insulin to take.

Health-care professionals use the “1500 rule” to calculate insulin sensitivity factor for people who use Regular (short-acting) insulin. The 1500 rule works as follows: Divide 1500 by the total daily dose of Regular insulin, in units. For example, if a person’s total daily dose is 30 units of Regular insulin, his insulin sensitivity factor would be 50 (1500 ÷ 30). So one unit of Regular insulin would be estimated to lower his blood glucose by 50 mg/dl.

Health-care professionals use the “1800 rule” to calculate insulin sensitivity factor for people who use the rapid-acting insulin analogs lispro (brand name Humalog) and aspart (NovoLog). (The 1800 rule is also expected to apply to the recently approved rapid-acting insulin analog glulisine [Apidra].) This is done by dividing 1800 by the total daily dose of rapid-acting insulin. If the total daily insulin dose is 40 units, the insulin sensitivity factor would be 1800 divided by 40, or 45.

Insulin sensitivity factor can be calculated only for people with Type 1 diabetes. It cannot be calculated reliably for people with Type 2 diabetes, whose pancreases often still make some insulin and who have varying degrees of insulin resistance.

Good luck friend, Angie

alwaystryin 2009-03-24 12:32:58 -0500 Report

I am by nature always tryin. This aspect of the discussions are profoundly informative. I first became aware of the sensitivity factor when researching the 450/500 rule for insulin per carb intake. I am not aware that this pertains to the insulin per drop in BSug levels.

lipsie 2009-03-13 10:44:51 -0500 Report

I don't know the answer to this question sorry, but I do have a question if you don't mind…what does that mean? I never heard of insilin sensitity number…I am on sliding scale, does it has anything to do w/ that? I USE to be on it regular at one point to and I still dunno whatcha mean..sorry Thanks, sorry you're so stressed out and I totally understand having to get straight before surgery…I do wish you well there. Sheila

dj7110 2009-03-13 11:14:13 -0500 Report

its on like a sliding scale equation used for fast acting insulin. when I first started the humalog I was told mine was 22 and use that, but never told on how they came about figuring out they came to 22.. the way I take my humalog is step 1 (Current Blood/Sugar reading minus 100)divided by 22 (ISF). step 2 add up my carbs with my meal and divide the carbs by 10. step 3 add both numbers from step 1 and step 2 togeather which equals amount of units of humalog I take with my meal. I do this for breakfast, lunch and supper.

vgarrison 2009-03-13 12:58:03 -0500 Report

Wow it sounds like you have to go thru alot to figure out what you have to take in order to eat. Have you asked your doctor what it is…and I don't know if I'm right or not, but if your not bottoming out or anything then maybe 22 is the right number…I mean if it was too high then wouldn't you be giving yourself too much insulin and then going too low?? Just an idea..

Blessed Be

dj7110 2009-03-13 18:13:16 -0500 Report

I have been running consitantly too high. other than the 2 readings, a 198 and 176 all my readings for the past couple weeks or so have been either in the 200's or 300's

vgarrison 2009-03-13 20:59:12 -0500 Report

Oh my DJ I would say that you do need to be adjusted…please talk to your doctor…let us know how its going please…

Blessed Be

alwaystryin 2009-03-24 13:15:19 -0500 Report

In short order, I recently espoke with the 'co-inventor' of the Spreadsheet, Mr. Dan Bricklin, for a Book still in progress.

The relevant part of that discussion offers this food for thought. 'Software' as we know it today was litigated to determine that the 'computer' itself was nothing other than a number cruncher, fueled by the method of delivery.

The pure of amount of equations suggested by your regiment takes me to a post from a younger sufferer of this disease.

She ponders why bury yourself in a sea of not seeing the forest through the trees? Just do what you know, when you know it, and that with the regiment, will make you…

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