By NormaJean Latest Reply 2009-02-26 14:05:20 -0600
Started 2009-02-25 14:36:37 -0600

Has anyone used or is using Actose for type 2 Diabetes,what's the
difference between Metformin and Actose,are there any side effects…all comments welcome..

7 replies

kdroberts 2009-02-26 13:53:57 -0600 Report

Actos is an insulin sensitizer so it is one of the only drugs to actually target insulin resistance. It also has a favorable effect on cholesterol. It can cause weight gain and edema and has a black box warning (inherited from avandia) about congestive heart failure. It's very expensive and takes a long time to actually work/stop working. One of the ways it works is to make your body grow new fat cells that are more sensitive to insulin.

Metformin primarily works with the liver to inhibit it storing and releasing glucose. It also helps, to a lesser extent, with insulin resistance.

Amy Togtman
Amy Togtman 2009-02-26 14:05:20 -0600 Report

wow i did not know that it could cause edema. cuz i was just told by my dr that i have edema in my feet and legs. i have poor circulation and neuropathy and i cannot feel my feet at all. I have cellulitis in both my big toes caused by cuts on both toes that i did not feel. And that caused the edema also. thank u for the insite on Actos kd.


NormaJean 2009-02-26 11:03:14 -0600 Report

Thanks for sharing your comments with us…I will go on the website and check it out…

Amy Togtman
Amy Togtman 2009-02-26 12:10:25 -0600 Report

I am on Actos have been taking it for 2 months now and with the combination of Actos and Levemir insulin and Novolog my blood sugars have never been better! My A1c was 5.8. Actos is the best!

rbergman 2009-02-25 23:22:39 -0600 Report

I used to be on Actose but was taken off because of family history with heart disease and congestive heart failure. While on it I felt it worked well for me though.

SkipT 2009-02-25 21:18:38 -0600 Report

You can check out both of these drugs at
They also have an interaction system that will let you check out all medication you might be taking.

Two painful feet
Two painful feet 2009-02-25 21:02:28 -0600 Report

I was only able to use metforman for a week. It made my stomach hurt so bad (but I have gastro paressis). I'm on Actos now and it keeps my sugars way down between 120 150. Once in awhile my bs shot up but being sick causes that.

Your Friend

Next Discussion: Say Hello.......... »