Blood Pressure Meds and Grapefruits

By GabbyPA Latest Reply 2010-12-15 12:13:01 -0600
Started 2009-02-17 17:17:46 -0600

I had read that grapfruits might not allow your blood pressure medicne work propperly. I asked my doctor today about it and he said no grapefruit for me. I was so bummed…another food to forgoe.
I thought that I would share this because I know many of you are on the same thing as I am, Lisinopril.

30 replies

jewelforshey 2010-12-15 02:35:16 -0600 Report

ok i do not like grapefruit wondering why my doc never said a word just failed my sugar test hum all he said was you have type 2 heres a class you must take and go get some blood test done thats it really uaaarrggg help

GabbyPA 2010-12-15 10:47:34 -0600 Report

I did not find out from my doctor's initiation. I read it somewhere and asked him about it. Here, I had been eating a grapefruit every morning they were in season before I found this out. They don't offer much, you really have to get in there and ask the questions.

CaliKo 2010-12-15 11:07:30 -0600 Report

I told my father-in-law that he perhaps shouldn't be taking his blood pressure medicine (same kind I'm on) with his morning orange juice or grapefruit juice. He just kept on doing it, because, after all, I'm just a girl and not a health care professional. (Urg) I suggested he speak with his pharmacist.
(When my son was young, he thought a pharmacist was someone who helped out on a farm! :-))

GabbyPA 2010-12-15 11:18:10 -0600 Report

For some reason it is only grapefruit juice that does it. There is something in the chemical make up of the fruit. OJ doesn't seem to be a problem.

CaliKo 2010-12-15 11:34:39 -0600 Report

Oh, great. I'm reading about it and says diabetics aren't supposed to take it…

CaliKo 2010-12-15 11:31:19 -0600 Report

I should look it up, then, my pharmacist said to wait 30 minutes after taking it before drinking or eating any citrus. It's Lotrel. My father-in-law drinks different juices with breakfast. Thanks.

joni55 2010-12-15 10:58:49 -0600 Report

I don't think my doctor told me either. I had to read it somewhere. I am finding that my doctor is not real helpful with giving me information or even following up with me on tests.

Susanpwd2 2010-12-13 14:06:52 -0600 Report

Grapefruit reacts to some medication is why you can't have it. I love grapefruit as well. The reaction is stronger on cholesterol medication but not sure.

jim hammock
jim hammock 2010-12-13 12:25:51 -0600 Report

l am also on Lisinopril and metformin.l take the blood pressure medicine at night right before turning out the lights and metformin at breakfast.Have my grapefruit about 11am as a snack.

GabbyPA 2010-12-14 18:19:37 -0600 Report

I asked him about that. I take my lisonipril at night also, but he said no grapefruit at all, no matter how far apart the time is.

Sheryl 2009-02-19 15:41:41 -0600 Report

Hi Gabby,
I just deleted my reply, I should have read the entire thread before jumping in…silly me…
I think grapefruit should be off everyones list…

Meridian - 26751
Meridian - 26751 2009-02-19 07:44:09 -0600 Report

It seems like all of my meds warn not to take such-and-such or so-in-so while on this medication. My water pill warns me to not go in direct sunlight. Tell that one to my wife when the lawn needs mowing! I have given up grapefruit because of my meds. and really don't miss it after 10 years.

Pauline B
Pauline B 2009-02-19 13:14:20 -0600 Report

I don't pay any attention to the sunlight warning's either. As a Seattle resident, we relish the sun!

jaclyncrystal 2009-02-19 14:14:04 -0600 Report

I understand the sun warning, I am a sun lover before all these meds and I will be for a long time, now I am off to get a tan, those wonderful lights go right through to my freezing bones (lol)jackie

jaclyncrystal 2009-02-19 00:38:40 -0600 Report

Most of my meds come from the drug store with the warning do not use grapefruit, and I used to love it, but have not had any for about 10+years :( jackie

Pauline B
Pauline B 2009-02-19 00:21:09 -0600 Report

Re Grapefruit: As Food Service Director in a psych hospital, I was directed by the medical doctor to not have fresh or canned grapefruit of juice in the house as it interferred with several of the psychiatric drugs. This annoyed the staff; both staff and patients shared the same cafeteria and foodline.

Personally I still eat grapefruit though I take medicine for high blood pressure. I figure that the effect will lower my blood pressure a little bit more. I don't know what the half-life of the meds are. I don't eat very much grapefuit.

Lisa Ann
Lisa Ann 2009-02-18 16:47:09 -0600 Report

That really sucks. I take Lisinopril and I love grapefruit. I usually eat one like an orange. guess I won't buy anymore. :(

2rs 2009-02-18 14:00:27 -0600 Report

I took it for almost 2 years, then began getting a nagging little tickle in the back of my throat that eventually became a constant caugh - so bad that I couldn't sleep or hold a conversation. Fortunately, while in the checkout line, the lady behind me told me that she had encountered the same problem & asked if I was taking Lisinapril!! sure, enough, my Dr. said it was a side effect & put me on Cozaar. The cough went away within a week.

2009-02-17 21:56:24 -0600 Report

If anyone is on cholesterol medication (Statins) they should avoid Grapefruit as well and here is why.

Grapefruit juice is one of the foods most likely to cause problems with drugs, because it is metabolized by the same enzyme in the liver that breaks down many drugs. The cytochrome P-450 3A4 enzyme breaks down grapefruit juice into useful components for body, just like it breaks down dozens of medications. When the system is overloaded, the grapefruit juice can “swamp” the system, keeping the liver busy and blocking it from breaking down drugs and other substances.

Drugs that use the same pathway and interact with grapefruit juice target some of the most common health problems doctors see today. The list consists of more than 50 medications, including some drugs used to treat high cholesterol, depression, high blood pressure, cancer, depression, pain, impotence, and allergies.

Scary that a simple fruit can cause so much damage. People have died from not knowing this!!!


Anonymous 2009-02-17 17:41:51 -0600 Report

I am also on blood pressure medicine but my doctor said I can have them occansionally but just not with the medication. So if I want the fruit or the juice I eat it as a snack in the afternoon because I take my med in the mornings.

Ashalka 2009-02-17 18:04:26 -0600 Report

Great idea, I hadn't thought about it as a snack in the afternoon or evening I had just stopped eating them.

GabbyPA 2009-02-18 10:08:57 -0600 Report

I asked my doctor if I could have half of one for breakfast because I take my Lisinopril at night, but he said no. It was better to just not eat it.

2009-02-17 17:29:00 -0600 Report

I am on blood pressure medicine and I'm not allowed grapefruit either. Even though I didn't eat it alot, I do like grapefruit, so I too am bummed about it.

highlandcitygirl 2009-02-17 17:21:19 -0600 Report

yes, i haven't had grapefruit in over five years. i was really fond of the red grapefruit juice!

GabbyPA 2009-02-17 17:24:34 -0600 Report

I just bought a bag of "flame" grapefruits at our local market. We have eatten half of the bag so far, so I suppose I will finish it, and then just not buy anymore. It really sucks, grapefruit is a citrus that I like a lot. Oh well, back to lemons and limes.

I wonder why just grapefruit is a bother? There must be something in it that other citrus doesn't have. I will have to look into that more.

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