Metformin Dosage

Evy135
By Evy135 Latest Reply 2008-08-03 05:51:24 -0500
Started 2008-06-02 16:48:43 -0500

Today I got diagnosed with Diabetis Type II. Dr. order was to take Glyburide 5mg AM and Metformin 500mg in the evening only 1 x 3 days and then I have to take it twice a day.

When is the best time to take the second one, with the Glyburide or later in the morning?


13 replies

ncnurse1459
ncnurse1459 2008-06-11 13:46:17 -0500 Report

Call your doctor first to clarify his/her orders. You can always ask the pharmacist to make sure. Since most of us have several doctors and only one pharmacist, he/she knows what you are taking and the best time. I take 2000mg daily, 1000mg each morning and 1000mg at bedtime. Hope this helps.

seawolf1944
seawolf1944 2008-08-03 02:01:15 -0500 Report

Hello Everyone,Everyones body system is different. Therefore, one doctor may prescribe on doseage for one diabeticand certain times of the day to take the med. Another doctor may prescribe the same med for a different patien and a different time for that patient to take their med.in other words, the same med might work better for one patientat a certain time than another patient at another time Its all about controling that fiesty,ornery old blood sugar level. My doctor has me on 1000 mg/Metformin/30 minutes before breakfast and 1000 Mg. Metformin/30 minutes before the evening meal. My doctor said this allows my med to be in my system in time to control my bllod sugar before my food gets digested. This works beautiful for me. It might not work the same way for another diabetic. A diabetic should try to set up a certain time for breakfast,noon meal and evening meal. There should be the same number of hours between each meal. I understand that with the fast pace of life as,We know it today,It might be hard to keep a strict meal schedule. You might require salads or whole wheat snacks between meals. In the past,I have worked with diabetics before,Who wereon insuln injections,Who had to carry different types of snacks to eat between meals. The body system (parts wise) of most humans are set up the same.However.Somewhere down through life,There may be a train wreck(with the function of a persons system) in a persons life. A doctor might prescribe same med for he or she and another doctor might prescribe same med for another diabetic at a different time of the day. as previously stated by another diabeti get your self a good support group,Who are medically qualified(diabetic wise) and follow their instruction. If,You are over weight,get on a good diet and lose some weight. I hope tha,I have offered some insight.John

kdroberts
kdroberts 2008-08-03 05:51:24 -0500 Report

"Hello Everyone,Everyones body system is different. Therefore, one doctor may
prescribe on doseage for one diabeticand certain times of the day to take the
med. Another doctor may prescribe the same med for a different patien and a
different time for that patient to take their med.in other words, the same med
might work better for one patientat a certain time than another patient at
another time Its all about controling that fiesty,ornery old blood sugar level.
My doctor has me on 1000 mg/Metformin/30 minutes before breakfast and 1000 Mg.
Metformin/30 minutes before the evening meal. My doctor said this allows my med
to be in my system in time to control my bllod sugar before my food gets
digested. "

You're right about peoples system being different, however your doctors orders are a little strange. Metformin isn't a drug that works from pill to pill, it takes a good few weeks to build up to therapeutic levels and will slowly reduce when you stop taking it. Taking it 30 minutes before a meal (according to research) could make it less effective, if you had stomach side effects it could also make them worse. It also really doesn't help with meal time numbers since it primarily works with your liver to stop it absorbing and releasing glucose. You would probably find that if you stopped taking it for a couple of days, maybe even 3 or 4, that you would notice very little difference in your numbers. 1000mg is also below the official general effective therapeutic amount (1500mg) and is usually used as a stepping stone to get to your therapeutic level.

If it works for you that's great, but you may find you can make it work better or that you may even not need to take it at all with a little bit of experimentation with your doctor.

Leigh Marsden
Leigh Marsden 2008-06-11 13:16:36 -0500 Report

Hello,
I take the same medications. I am under the assumption that you should take them together at the same time each day. the best thing to do is ask your Doctor. Good luck, Leigh

Ginetteb
Ginetteb 2008-06-10 01:59:45 -0500 Report

Evy, since you seem to know nothing or very little about this disease, PLEASE ask your doctor where you can go to get the basics about diabetes. Usually hospitals have classes on diabetes that cost nothing. I know that the hospital near my house offers these classes from time to time.
As for medication, use this site as a guide, but ask you doctor how to use the medicine.

This site is great and the members will give you feed back based on their own experience. When you mention a certain drug, you're gonna get a bunch of people telling you how they reacted to the drug, their side effects, etc. They will also give you all the encouragement and support you can imagine.

14 years ago, when I was told that I had to take insulin injections, my doctor ordered a home nurse to come to my house 4 times a day, before breakfast, before lunch, before dinner and at bedtime. Not only did she show me how to give myself the injections, she also taught me a lot about diabetes, how it affects my body and how to deal with it to avoid complications.

So first things first. Ask you doctor about your medicine and find yourself a hospital that offers classes on diabetes.
Good luck.
Ginette

LeighG
LeighG 2008-06-10 05:46:30 -0500 Report

i had someone come out when i found out i had it when i was preg. thats how i learned a good deal. htne after baby it went away and come back for good four years later.point being ,being able to havbe that person come out and talk with you and teach is one of the best ways to learn i beleave.it helped me alot.

Evy135
Evy135 2008-06-03 14:56:22 -0500 Report

Thanks for your answers Bren and kdroberts!

This is so new to me!

NITROGIRL
NITROGIRL 2008-06-09 18:36:23 -0500 Report

Most doctors advise that you take all your metformin at one time in the evening before bed. This is one of the few diabetes meds that will not cause low BS and when taken at night it helps protect your kidneys and liver from damage.

kdroberts
kdroberts 2008-06-10 01:25:59 -0500 Report

I've never heard a doctor suggest taking it at bed time, I would question the logic behind that too. If you take the XR version then you would take it all at once but the reason you take it with food is because it helps the absorption of it and it will drastically reduce the side effects. It is possible to get lows when taking metformin, I've had them. On the kidney and liver protection, I don't know. I'm not a doctor but I do know that metfromin comes with a warning not to take it if you have liver of kidney damage as those are the two primary locations it works in, the liver to reduce the amount of sugar stored and released and the kidneys to filter the medication out of you. I think the kidney warning is because you could get too much metformin in your body if you have reduced renal function and the liver warning is because that where it really does it's workings.

I'm always open to learn so if you have some sources about why you should take metformin at night and the kidney and liver protection, I'd definitely like to read them.

LeighG
LeighG 2008-06-10 05:43:56 -0500 Report

i agree with kdroberts.thats when my docter told me to take mine and i have never heard the take it all at once at night thing.my docter told me breafest and dinner are the good times to take it.but also open to learning more if that proves to be true.

tmana
tmana 2008-06-11 07:47:14 -0500 Report

When I was on Glucophage XR (before the generic) twice a day, I was told to take it with the morning and evening meals. My Other Half was told the same. When I reduced to once daily, it was in the mornings.

kdroberts
kdroberts 2008-06-03 00:14:30 -0500 Report

Most people who take metformin twice a day take it with breakfast and dinner, during the meal. That way you get the most efficient dose in your body and usually it helps tame some of the gastro side effects that many people suffer from.

Bren62W
Bren62W 2008-06-02 21:20:16 -0500 Report

Hi Evy,

This is something you would probably be best advised to ask your doctor or your pharmacist. Good luck.

Take care,
Bren