By jupton1 Latest Reply 2008-07-04 02:25:46 -0500
Started 2008-06-01 15:36:42 -0500

Trocho, C., et al., 1998. "Formaldehyde Derived From Dietary Aspartame Vinds to Tissue Components in vivo," Life Sciences, Vol. 63, No. 5, pp. 337+, 1998

"These are indeed extremely high levels for adducts of formaldehyde, a substance responsible for chronic deleterious effects that has also been considered carcinogenic.

"It is concluded that aspartame consumption may constitute a hazard because of its contribution to the formation of formaldehyde adducts."

"It was a very interesting paper, that demonstrates that formaldehyde formation from aspartame ingestion is very common and does indeed accumulate within the cell, reacting with cellular proteins (mostly enzymes) and DNA (both mitochondrial and nuclear). The fact that it accumulates with each dose, indicates grave consequences among those who consume diet drinks and foodstuffs on a daily basis." (Neuroscientist Russell Blaylock, MD)

39 replies

preacherman1611 2008-06-30 12:39:16 -0500 Report

Aspartame effects different people in different ways. Unfortunately, most of the effects are negative. My mother would get ulcers in her mouth. With me it causes a funny feeling in my mouth and I just don't want to take the risk. I prefer Splenda. As of yet I have had no negative side effects and it does make food taste good.

Elfin 2008-07-02 12:55:56 -0500 Report

I am cutting out as much asparatame as possible from my diet. I think it does contribute to low energy and weight gain.
About Splenda…As I understand it, Splenda breaks down into chlorine! Chlorine is a serious poison and even if the amount is relatively low, it just seems like we should avoid it as much as possible.
I am coming to the conclusion that the only safe sweetener is plain old sugar, limited to very low usage. I caution you to look at the ingredients, not just the nutrition facts.
I am astounded at the amount of sugar in our canned,processed and so called diatetic foods. It is used in these foods as a perservative.

jupton1 2008-07-02 13:59:15 -0500 Report

I agree Splenda & aspartame are both bad..I think after reading several pages Ill stick with water..JohnU

Elfin 2008-07-02 16:10:38 -0500 Report

Yeah water is great with a little lemon or lime juice added. So I get good taste, not much change in nutritional values and a bonus of Vitamin C (LOL)

NyxWulf 2008-07-03 05:55:48 -0500 Report

To create Splenda they take a regular sugar molecule and replace all the carbon atoms with chlorine atoms. Supposedly it will just pass harmlessly through your system. I've been a little freaked out by that ever since it launched.

To be honest, I'm way more freaked out by Splenda than Aspartame, but that's just me.

Elfin 2008-07-04 02:25:46 -0500 Report

You know I think the operataive word is "supposedly". I am tired of things that are supposedly good for me! I wish I could avoid all things that are bad for me, but when they are unidentified or reported to be OK, I am very suspicious. I hope paranoia isn't a side effect of asparatame and Splenda LOL

Elfin 2008-06-30 04:43:22 -0500 Report

I have just recently learned about the dangers of aspartame! I had heard in the past that if you drink diet sodas you will be fatter in a year. Now I see that as the effect of aspartame.
I am concerned too about the formaldehyde, if it accumulates in your body, is there a way to get it out?
What good is the FDA if they can be bought out and refuse to address the complaints?

jupton1 2008-06-30 05:32:57 -0500 Report

I agree I dont trust the FDA any longer..There is to much proof,even splenda is bad for Us..John

preacherman1611 2008-06-30 12:47:18 -0500 Report

What are the negatives concerning Splenda. I have not really heard of any and I like the way it makes my food and drinks taste.

NyxWulf 2008-06-05 03:12:55 -0500 Report

jupton1 I know your intentions are good, but there is a lot of misinformation about aspartame out there. Please post some links to credible medical sources to back up your claims about the dangers of aspartame. I've only seen a few studies that have been widely debunked and ridiculed by the medical community at large. All serious medical studies that I'm aware of have shown there are no short term or long term dangers of aspartame use.

If you read this snopes article you can find links to numerous different medically relevant research studies:

Aspartame does indeed break down into formaldehyde etc, however the amount of aspartame is quite small in a soda. Something else to know is that fruits also break down into formaldehyde derivatives, and they do so in much higher quantities than aspartame ever could. In fact quite a few foods break down into that same path, and most of them do it in vastly greater quantities than aspartame.

There is a lot of fear mongering out there, but the reality is that aspartame is an *excellent* substitute sweetener for diabetics. It's much better to have aspartame or splenda than sugar. Certainly water is the best, but honestly I am highly skeptical about the claims you've posted about aspartame.

jupton1 2008-06-05 04:19:48 -0500 Report

Read the 2007 study,the FDA has tried to cover up this drug for years…There are over 50 pages of bad things about aspatame..I work with several Mds,PDhds ,Rns and >all agree< this is unsafe,just my view..theres alot of facts,Make sure You read who wrote the review on each view…Just my view…:)Im 100% sure the people who make Aspartame will say its safe…NyxWulf I respect Your view,what concerns me is the 2006 view you just posted claiming this is safe..Please note the dates…

jupton1 2008-06-05 04:24:27 -0500 Report

NOTE this is 2007>>>>>>>New Study by Ramazzini Institute Confirms Aspartame Carcinogenic

Dr. Morando Soffritti of the European Ramazzini Foundation will present the results of a new study confirming the carcinogenicity of Aspartame on April 23, 2007 at the Mount Sinai Medical School of New York, where he also will receive the prestigious Irving J. Selikoff Award.

Aspartame, the artificial sweetener made by Searle/Monsanto was found to cause cancer in laboratory animals already in the original studies that were submitted to the FDA when approval was asked to put it on the market. The justified doubts of the FDA's scientists were overridden when Donald Rumsfeld called in his political markers.

Another study conducted in Spain by Trocho et al came to similar results, identifying a transformation of parts of the molecule into formaldehyde as a probable cause. Later, a study of the European Ramazzini Foundation confirmed the sweetener's carcinogenicity in laboratory rats and seriously questioned its safety. But industry, through the European Food Safety Authority, succeeded in diverting attention from the damaging findings, calling them an artifact of the study's design.

Now, a new, long-term study on Aspartame has been completed giving lower dosages but confirming, once again, the carcinogenicity of the sweetener. See the announcement from the Ramazzini Foundation here:

- - -

New aspartame data to be presented at Mount Sinai School of Medicine in NYC, USA

(Original here)

A second study conducted by the European Ramazzini Foundation (ERF) confirms the carcinogenicity of aspartame. The results of this study will be presented April 23, 2007 at the Mount Sinai Medical School of New York, where ERF Scientific Director Morando Soffritti will receive the third Irving J. Selikoff Award.

Aspartame is an artificial sweetener consumed by hundreds of millions of people worldwide. It is used in over 6,000 diet products including soft drinks, chewing gum, candy, desserts, yogurt as well as in pharmaceuticals, in particular, syrups and antibiotics for children. In 2005, the European Ramazzini Foundation published important experimental data demonstrating the carcinogenicity of aspartame. These data demonstrated for the first time that aspartame is a carcinogenic agent, inducing various types of malignant tumors in rats, even at dose levels currently considered acceptable for humans.

As soon as carcinogenic effects were perceived during this first study, the ERF began a second long term experiment, administering aspartame at low doses in feed to rats beginning during fetal life.

In a world exclusive, Italian news station TG2 announced on April 13th that the European Ramazzini Foundation will present the results of this second study at the Mount Sinai School of Medicine at the end of April when Scientific Director Dr. Morando Soffritti will receive the third Irving J. Selikoff Award. The news story may be viewed at:

- - -

The FDA has long known of the damaging nature of the sweetener. At one time, it published a list of 92 diverse side effects and in part serious reactions to consumption of the stuff.

Here is what Betty Martini, who has been warning tirelessly of the toxicity of Aspartame, says about the FDA's list:

Aspartame illegal

As many may know, aspartame is on the market illegally. It's adulterated as discussed by the National Soft Drink Assn (now American Beverage) and in the congressional record. Because you cannot ship an adulterated product for sale it, therefore, violates Interstate Commerce. Dr. Adrian Gross, FDA toxicologist, told Congress that aspartame violated the Delaney Amendment which forbids putting anything in food that caused cancer in animals. It's also a drug, an addictive excitoneurotoxic carcinogenic drug that interacts with all drugs and vaccines, and is masquerading as an additive.

NyxWulf 2008-06-05 04:52:20 -0500 Report

The European Ramazzini Foundation's two studies have been *thoroughly* debunked. Look at the wikipedia article under Aspartame Controversy and look under recent research:

Here are some quotes for you: first by the European Food Safety Authority - "The EFSA's press release about the Ramazzini study,[72] published on 5 May 2006, concluded that the increased incidence of lymphomas/leukaemias reported in treated rats was unrelated to aspartame, the kidney tumors found at high doses of aspartame were not relevant to humans, and that based on all available scientific evidence to date, there was no reason to revise the previously established Acceptable Daily Intake levels for aspartame."

From the FDA: "Based on the available data (…) we have identified significant shortcomings in the design, conduct, reporting, and interpretation of this study. FDA finds that the reliability and interpretation of the study outcome is compromised by these shortcomings and uncontrolled variables, such as the presence of infection in the test animals"

New Zealand Food Safety Authority (NZFSA) published a press release commenting upon the Italian study: "… These studies were conducted in a way that could not possibly have provided any information about the toxicity of aspartame – or in fact anything else in the rats’ diet. The animals used were allowed to live until they died naturally, meaning that all the study did was show the results of ageing, which as we all know is a natural process that leads, inevitably, to death.
In fact, the only conclusion that can be drawn from the results is that aspartame appears to be safe because the studies showed that those rats fed it (even at very high doses) lived as long (if not longer) as untreated rats, despite consuming up to more than 100 times the ADI every day of their lives. If aspartame was as horrendously toxic as is being claimed, it would be logical to expect the rats dosed with it to have shortened life-spans. The conclusions drawn by the researchers were clearly not backed up by their own data."

Importantly the Ramazzini Foundation study only deals with Rats. The widest, longest and most comprehensive study of Aspartame in *Humans* was conducted by the National Cancer Institute in 2006. "A study published in April 2006 sponsored by the National Cancer Institute involved 340,045 men and 226,945 women, ages 50 to 69, found no statistically significant link between aspartame consumption and leukemias, lymphomas or brain tumors."

If the Ramazzini Foundation is your source of information, you should probably broaden your research to consider other more respectable sources. Their research has been widely debunked and criticized.

Just because you work with MD's and Nurses who believe that doesn't mean anything other than anecdotal support for your position.

I suppose you can believe there is some vast conspiracy that controls all of the food agencies around the world and the cancer institute of the U.S. who are all in agreement and the Ramazzini Foundation is the one truth telling group in the world. Or you can take the alternate simpler explanation which is that aspartame isn't harmful and the Ramazzini study which didn't even show a decreased life expectancy for Rats let alone humans is flawed. Personally, I'm convinced their study is flawed.

jupton1 2008-06-05 05:35:54 -0500 Report

Date of Your post and the date of the Study was> study published in April 2006.John…2008> International Scientists Conclude Sweetener Is Safe Across Population Groups.”
What these press releases did not tell readers is>> that this review was funded by the aspartame manufacturer, the authors had serious conflicts of interests, and in page after page after page of the review, research was misrepresented and important research and information was omitted from the review. This analysis is intended to help readers understand how manufactures pay for and get published reviews that put their toxic products in a positive light.

jupton1 2008-06-05 05:04:33 -0500 Report

IN WAR LAWS ARE SILENT…JOHN..NOTE THERE ARE 100s of pro pages and 100s Cons..If people trust the FDA then they should use ASPARTAME…I believe the quotes You put was from 2006,this one I posted is from > APRIL 2008,
HERE is a NEW REVIEW 2008>>New review

Writing in the European Journal of Clinical Nutrition, a Nature journal, the scientists behind the new review state: "The aim of this study was to discuss the direct and indirect cellular effects of aspartame on the brain, and we propose that excessive aspartame ingestion might be involved in the pathogenesis of certain mental disorders, and also in compromised learning and emotional functioning."

The researchers found a number of direct and indirect changes that occur in the brain as a result of high consumption levels of aspartame, leading to neurodegeneration.

They found aspartame can disturb the metabolism of amino acids, protein structure and metabolism, the integrity of nucleic acids, neuronal function and endocrine balances. It also may change the brain concentrations of catecholamines, which include norepinephrine, epinephrine and domapine.

Additionally, they said the breakdown of aspartame causes nerves to fire excessively, which can indirectly lead to a high rate of neuron depolarisation.

The researchers added: "The energy systems for certain required enzyme reactions become compromised, thus indirectly leading to the inability of enzymes to function optimally.

"The ATP stores [adenosine triphosphate] in the cells are depleted, indicating that low concentrations of glucose are present in the cells, and this in turn will indirectly decrease the synthesis of acetylcholine, glutamate and GABA (gamma-aminobutyric acid)."

Furthermore, the functioning of glutamate as an excitatory neurotransmitter is inhibited as a result of the intracellular calcium uptake being altered, and mitochondria are damaged, which the researchers said could lead to apoptosis (cell death) of cells and also a decreased rate of oxidative metabolism.

As a result of their study, the researchers said more testing is required to further determine the health effects on aspartame and bring an end to the controversy.

Source: European Journal of Clinical Nutrition
2008, doi: 10.1038/sj.ejcn.1602866
"Direct and indirect cellular effects of aspartame on the brain"
Authors: P. Humphries, E. Pretorius, H. Naude

NyxWulf 2008-06-05 05:34:59 -0500 Report

I'm not sure who John is, or who you are referring to.

Their findings are based on previous studies. Go read the wikipedia article I posted above if you care about reading a more balanced perspective. The Ramazzini Foundations data does not support their conclusions. Their simply is no data that supports their wild speculations.

jupton1 2008-06-05 05:37:18 -0500 Report

Dates of Your quotes >Ramazzini study,[72] published on 5 May 2006,>> Mine was 2007 & 2008…It just 1 view,the people can choose what they trust..Your friend, John

morris.js 2008-06-05 05:55:45 -0500 Report

In my opinion, you both have posted enough studies for us to research and interpret on our own… As far me, I agree that there is enough to prove that Aspartame is dangerous in high levels. But having said that, I do not have any fears about drinking the 1 or 2 Diet sodas a day. The Aspartame levels in those couple of sodas is much better for my body than the alternative things I would be drinking, (mostly coffee).

Barbi187Girl 2008-06-03 03:18:56 -0500 Report

ok i have high blood sugars and when they regulate to where they need to be then i feel worse that when the too high. I guess its being used to being too high.. I was diagnoised in 2001, but i think I became diabetic in 1995. Im currently taking glipized 10mg er, and im going to ask to be put on this medicine januvia, its like advandia but im hearing it helps you more. for my height being 5'4 my weight needs to be 130. Since jan 2, 08 i have lost weight from 240lbs to 207.

Ginetteb 2008-06-03 00:08:31 -0500 Report

Boy, am I glad I prefer and drink water all day long. I rarely drink diet soda.
I will be sure to remind everyone I know about the side effects of diet sodas.
Thank you for the research and sharing this information. This should be on the news on every TV channels so everyone knows what they are dealing with when they take a drink of diet soda.

jupton1 2008-06-01 15:38:36 -0500 Report

Anyone that wants to no the truth about Aspatame check this site..>

Goddess 2008-06-01 17:56:34 -0500 Report

I just want to know how it effects the body. What kind of damage does it do to a person? Thank You

jupton1 2008-06-02 00:58:59 -0500 Report

I left a link ,I couldnt list all the bad things this does,Cancer ect..Copy & paste the link I left…This product is in about 60% of the diet pops and sweetners.>.

JP - 14811
JP - 14811 2008-06-02 01:41:00 -0500 Report

Hello and good morning to all. Aspartame.. wow where do I begin!! I have used this sweetner since it was introduced many years ago.. I was diagnosed with Fibromyalgia 3 years ago which is a painful illness and at the time I could hardly walk. They at first thought I had MS or Lupus. I went through gruelling physical therapy for almost a year and then was given stretching exercises to do on my own and took muscle relaxers daily.
Well, after reading about aspartame and the 'possible' effects it can have on your body I started an experiment of my own. Over the last year, I have 'detoxed' myself from aspartame, gradually and moved back to Sweet and Low for sweetening foods, I will use Splenda also if I have to. The results after my year of 'detox'? The Fibromyalgia is almost nonexistent, at least 80-90% gone!!! I have no muscular pain, no throbbing pain in my limbs. The only symptoms that remain are the fatigue and slight pain from touch, even those are about 75% less than they used to be. I still get the 'exhaustion days' but now it's about 2-3 times a YEAR instead of every other week. My conclusion is that the aspartame was the culprit and who knows what damage it could have done that may be permanent. I've seen my rheumotologist and he is amazed at the change in symptoms. 3 years ago, I could hardly walk and now I'm exercising 5 hours a week and feeling great.
Just my information on it.

JP - 14811
JP - 14811 2008-07-03 02:34:56 -0500 Report

Update: One month later!! I am one more month into detox from Aspartame poisoning (Dr's term) and ALL my symptoms are gone.. I am feeling better than I have in my adult life!! No pain, no fatique, no IBS, nothing..

Living proof that "SOME" people are affected by Aspartame not all! Those that are affected by it can be seriously ill, even die. Splenda is now coming under scrutiny so I avoid that too. I am now using blue agave nectar in my coffee, it's natural, it's organic, and it tastes good (like sugar). No affects on my blood sugar either.


*Judy (JP)

jupton1 2008-06-02 14:35:22 -0500 Report

12 Environmental Health Experts Call for Aspartame Review and Possible Ban

SCIENCE VOL 317 6 JULY 2007 page 31
Souring on Fake Sugar

Fearful it causes cancer, 12 U.S. environmental health experts last week asked the U.S. Food and Drug Administration (FDA) to review the potential health risks of the artificial sweetener aspartame, which appears in everything from medicines to diet sodas.

A study published last month in Environmental Health Perspectives found somewhat more leukaemias and lymphomas in male rats receiving less aspartame than the recommended maximum for humans; at higher doses, the rats had a marked increase in cancers throughout the body.

The letter from the 12 U.S. environmental health experts can be found at:

jupton1 2008-06-02 16:17:49 -0500 Report

..If you're like most people, you reach for a sugar substitute because you've been told it's good for you-that it would save you from the evils of sugar, and that it would even help you trim off those extra pounds. But, like all of us, you've been lied to.
So let me set the record straight now. Aspartame is one of the most dangerous substances ever added to food. Not only has aspartame been proven to make you fatter, it's been proven to cause some pretty serious diseases, not the least of which are cancer and neurological diseases.

And the proof is on file already. Aspartame has brought more complaints to the FDA than any other additive-ever. It's responsible for a full 75 percent of the complaints the agency gets. From 10,000 consumer complaints, the FDA compiled a list of 92 symptoms, including death..In 1997 there was an increase in aspartame users reporting severe toxicity reactions and damage such as seizures, eye damage and vision loss, confusion, severe migraines, tremors, depression, anxiety attacks, insomnia, etc. In the same years, Ralph Walton, MD, Chairman, The Center for Behavioral Medicine showed that the only studies which didn't find problems with aspartame where those funded by the manufacturer (Monsanto). Given the agreement amongst independent scientists about the toxicity of aspartame, the only question was whether the formaldehyde exposure from aspartame caused the toxicity. That question has now been largely answered because of research in the late 1990s.

The following facts shown by recent scientific research:

Aspartame (nutrasweet) breaks down into methanol (wood alcohol).

Methanol quickly converts to formadehyde in the body.

Formaldehyde causes gradual and eventually severe damage to the neurological system, immune system and causes permanent genetic damage at extremely low doses.

Methanol from alcoholic beverages and from fruit and juices does not convert to formaldehyde and cause damage because there are protective chemicals in these traditionally ingested beverages.

The most recent independent research in Europe demonstrates that ingestion of small amounts of aspartame leads to the accumulation of significant levels of formaldehyde (bound to protein) in organs (liver, kidneys, brain) and tissues.

Excitotoxic amino acids such as the one which is immediately released from aspartame likely increases the damage caused by the formaldehyde.

jupton1 2008-06-02 23:48:19 -0500 Report

I would just like to say that I work in a large Drug Rehab center,Im realy worried about this drug that the FDA fails to take off the market because they make money to turn their heads from the manufactor..This is my view,several Drs I no feel the same way..JU

jackie narron
jackie narron 2008-06-03 13:56:58 -0500 Report

Aspartame is one of the most toxic substances that you can put in your body. If your want a sweetner that is effective and naturally pure look for Stevia, you can usually find it in health food stores. It is about 300 times more concentrated than most sugars so you don't have to use as much and it is natural. But don't take my word for it, do the research for yourself-between using that and Splenda my A1C is now 5.9.

taz202020 2008-06-03 20:00:40 -0500 Report

jupton 1,
Do you have any information on what diet pops use other sweetners other than aspartame? I drink water and 3-4 diet pops each day for many years. Since we need to stay away from fruit juices and milk what alternatives are there if you can't drink diet pop? I use sweetner for everything (splenda)and it would be so hard to give up diet pop. Maybe someone has some info if you don't. I will also go to the site you suggested.

jackie narron
jackie narron 2008-06-05 14:22:32 -0500 Report

They are coming out now with some drinks that have Splenda in them. If you are going to a restaurant you can order Iced tea without sugar and then carry your own splenda with you. The sweetners that you want to avoid are sweet-n-low, equal, anything with saccarine in it. You have to make some changes to your diet but these little ones are ones that you can do! I feel a whole lot better saying that I am a person who has diabetes than I am a diabetic thats out of control. A lot of the companies that manufacture the artificial sweeteners know how to play on the fact that we too can become addicted to the chemicals that they put in our sodas and they know between the sugar addiction and the caffiene addiction they can keep us hooked and the FDA won't say anything because they are the ones bankrolling this effort. In the ideal world we would all drink water and thus we would not have to even question of what we should/or should not drink. Remember that FDA stands for Food and Drug Administration, They definately will condone anything that they can earn money from and they will like it even more if it causes a condition that you have to be on meds for. It is their job to not only regulate and monitor activities on the safe consumption of food (for which they receive monies), but to also regulate, manufacture, and distribute medicines to treat illness, Alot of those illness could be completely avoided had not the food part upheld the dignity of their office and inspected and had not let inferior quality pass through into public consumption. The drug aspect of this office should keep more stringent laws in regard to administrations of trial tests. We as a country need to be aware of what tests are conducted and we need to be activly involved in those tests.