Diabetes Meds Face FDA Scrutiny for Pancreas Risks

By jayabee52 Latest Reply 2013-04-01 14:35:30 -0500
Started 2013-03-26 13:06:12 -0500

From WebMD Diabetes:
By Lisa Nainggolan
Medscape Medical NewsMarch 14, 2013 — The FDA is looking into an increased risk of pancreatitis and precancerous changes to the pancreas from widely used drugs to treat type 2 diabetes.

The medications are called incretin mimetics, which mimic a natural hormone in the body that tells the pancreas to release more insulin after eating. Insulin, in turn, lowers the person's blood sugar. Included in this class are the drugs Bydureon, Byetta, Janumet, Janumet XR, Januvia, Juvisync, Kazano, Kombiglyze XR, Nesina, Onglyza, Oseni, Tradjenta, and Victoza.

Read more here ~ http://diabetes.webmd.com/news/20130314/diabe...=

Just thought those of you who are taking those meds might want to know.


28 replies

jigsaw 2013-03-26 17:18:32 -0500 Report

I have to agree with the crowd here! I felt the positives outweighed the negatives with some of the meds I was on. I have since had a change of heart!!! I suffered with constipation for quite sometime. I was told to look into gastroparesis, do more exersize, drink more fluids, take Metamucil, eat more fibre, etc etc etc. All this by numerous doctors. The problem stubbornly persisted. Finally, and recently I got off Metformin. After about two weeks or so, I feel like a new man! The constipation is completely gone. My digestive funtions are as efficient as they ever were. The doctors are standing around with there fingers up their noses. The Met was controlling my bg, but it was also wrecking my intestines!! That was the kicker for me. True, you can't stay healthy for long with high bg, but you can't live without intestines either. As of now, it's just insulin for me, and in addition to a healthy funtioning digestive tract, my bg is under control and hopefully I don't have to be as concerned about meds damaging my pancreas.

CHenry9973 2013-03-27 16:20:58 -0500 Report

I was on Metformin before I was put on insulin. Wish they had skipped the pills and just put me stright on the shots. They are easy to do, heck my 14 year old grandson gives me the shot when he is here. (with supervision, of course). I feel much better then I did.

lneider 2013-03-30 19:41:02 -0500 Report

I too was on Metformin prior to insulin injections I became Vit b 12 defiecient? never medically confirmed Metiformin was the cause, Linda

jigsaw 2013-03-27 18:12:57 -0500 Report

Glad your doing well on insulin also! I've heard many complaints over the years concerning Metformin. I have definitely joined the ranks with those who are leery of Metformin. I'll spare you the details, but I'll definitely never use it again!!!

jayabee52 2013-03-26 17:22:23 -0500 Report

I think the Drs had their fingers in another hole, a little further south!

Glad to hear you got it figured out!

Tony5657 2013-03-27 05:14:22 -0500 Report

Ahhhh James, you're quick on the draw AND you're bad. LOL

Lentyl 2013-03-29 11:30:51 -0500 Report

Yes. I think that the picture shows "pretty or beautiful" in terms of your relationship. something very special in that picture. Lentyl

jayabee52 2013-03-29 14:13:39 -0500 Report

I thank you for that Lentyl! It certainly was an extra special relationship for both of us, and I think it showed in her face in that photo.

We had gotten married before family and friends just minutes previously and I believe her happiness shows on her face.

She had never been married before at 54 yrs and thought she'd never be married. In fact that thought was so strong with her I had to assure her several times that I wasn't going to willingly go away like 2 previous fiancees did. If I went away it would be involuntary like death or incompacity.

God was gracious and we married. That thought was so stong with her that even after we were married she tried to push me away because she thought it wouldn't last. It was quite interesting to be involved with her. Sometimes terrifying to me when she did that. I didn't want to lose her, the best person who happened to me in quite a while.

It is a special picture to me!

Lentyl 2013-03-29 14:51:55 -0500 Report

A beautiful love story James. How wonderful that the two of you had the time to share it. Lentyl

Graylin Bee
Graylin Bee 2013-03-29 01:39:34 -0500 Report

James,use Google translate with extreme caution. My sis who lives in Khazikstan has had some strange google translate moments. Seems google picks one of various meanings of a word and then when you translate the word Google chose, it picks a different of that word's meanings. This has led to some very dramatic moments for some of her fellow ex-pats dealing with locals.

jayabee52 2013-03-27 06:09:19 -0500 Report

French for little ole "ME???" I know, It's lat for us both! about ready to turn in! (turn into what? you may ask — into a sleepy head ready for bed

Tony5657 2013-03-27 06:19:04 -0500 Report

You & I must be world's apart, so to speak. What state are you in? I'm just starting my day and you're ending yours. I'm just a COF (curious ol' far+)

Tony5657 2013-03-28 10:16:05 -0500 Report

OK Jigsaw, you and James are in the same category - you're bad - As the group ZZ Top sang "I'm bad, I'm nationwide" (or something like that) No I didn't make a typo. I was trying to keep this discussion PG. LOL Thanks for the laugh … laughter is good. I guess fart is a common word now, since I hear that I'm an old fart daily. At least I'm still above the ground & not pushing up daisies, poison ivy or something in between…
Ol' Tony still a kickin' in New Braunfels, TX

jayabee52 2013-03-27 07:39:14 -0500 Report

i am in Las Vegas, not all that far from you really. I just have my days and nights mixed up. when I wrote the above I was really tired and ready for bed, but when I laid my head onto the pillow I my mind turned on again and couldn't drop off. So I got up and started doing stuff around my apt, like making a chicken veggie soup in my crock pot for eating later today.

Tony5657 2013-03-28 10:22:42 -0500 Report

Yes James, with all those lights in "sin city" I'd get mixed up too (more than my usual mix ups). Last time I was in your city was 1968 - just got married and was on our way to Coronado Island, CA to live for awhile. Hey, I hear things in Vegas have changed slightly since 1968. By the way, next time you make chicken veggie soup, fax me some …
Ol' Tony, still keeping on, keeping on but not keeping on with this discussion :o(

Graylin Bee
Graylin Bee 2013-03-26 17:13:36 -0500 Report

Strengthens my resolve to keep figuring out which foods cause spikes. If I can continue to keep med free it's worth it. If my system decides to need more help I think I'd opt for insulin. Even though I know people have had adverse reactions, to insulin, overall I think it is safer than meds.

old biker
old biker 2013-03-26 15:54:16 -0500 Report

If I had to do it over again I would skip all the years I was on oral meds and go straight on insulin. I still worry about all the years I was on Actos another so called wonder drug for diabetes

jayabee52 2013-03-26 16:08:19 -0500 Report

I hear you biker! Because of all the problems with Rx meds I try to limit my use of most of them. I was put on Met as soon as I was Dx'd and I later found out I didn't really need it if I ate correctly. But too late I learned that and I got other complications from not having my BG levels corrected soon enough.

Pynetree 2013-03-27 07:14:40 -0500 Report

James and OldBiker…That is what scares me. I have been T2 for about 25 yrs..and on Metformin for all but 4 months in '05. But since my A1c's have been steady 5.4 to 6.4 for most of the time, except in those first years, Dr. says she is going to stay with the Metformin. Now I worry about the drugs affect on my organs for all these years.