By manapua72 Latest Reply 2013-01-30 16:08:45 -0600
Started 2013-01-24 12:55:11 -0600

Once again I'm confused !!!!!!!!! I know the deference between type 1 & 2 . What I don't know is can a 2 become a 1 or a 1 become a 2 … I'm reading people's post and not quite sure …

4 replies

KyleCoats 2013-01-30 16:08:45 -0600 Report

Type 1 is an autoimmune disease, you cannot be a diagnosed type 2 and become type 1. A type 1's immune system has attacked and destroyed insulin producing bets cells. Type 2 is when insulin receptors are blocked by fat cells. People who say you can go from 2 to 1 don't understand the fact type 1 is an autoimmune disease, it has no link to type 2. Fact.

GabbyPA 2013-01-25 10:38:49 -0600 Report

As James stated, they are different diseases with similar symptoms.

Generally a type 1 will always be insulin dependent as the pancreas is no longer functioning. There are procedures that replace the islets or the entire pancreas to help in the treatment of type 1, but a reversal or a jump start of the pancreas is not likely to happen.

However, like Shelly's story, a misdiagnosis can happen. You would think in this age, that would happen less often. So it's not really that she changed from a type 1 to a type 2, but that her diagnosis was incorrect in the beginning.

It is far more likely that a type 2 would evolve into a type 1, but I am not sure that it would be called that, but just keep the name of an insulin dependent type 2. Unless the autoimmune system attacks the pancreas and prevents it from working at all, type 2's are generally still type 2's.

There are always exceptions and the more we learn about this disease, the more we see how different they are. A type 1 may die without insulin to cover the glucose in their system, while a type 2 may die because no matter how much insulin they have, their system won't accept the function of it. They are both sides of a double edged sword.

jayabee52 2013-01-24 13:10:02 -0600 Report

A type 2 is a person whose pancreas is still producing some insulin. It is just the action of the insulin is blocked in many cases by insulin resistance.

So since the pancreas is working, it is able to be attacked much the same way as a person who has normalized BG responses would be when their pancreas is attacked by an autoimmune reaction against the Beta cells in the pancreas. OR the pancreas is damaged by an accident of some kind and the insulin production is severely compromised.

So yes, a T2 is able to become a T1, but as far as I know, a T1 cannot become a T2. If that happens, it would be a step toward curing T1.


ShellyLargent 2013-01-24 13:07:29 -0600 Report

I found this on Wkik Answers:

Not sure if it's 100% accurate, but sounds plausible…

In my case, I was misdiagnosed as a Type 1 because of my high A1c and protein spillage in my kidneys. I also was having symptoms (looking back from my diagnosis date) for well over 10 years prior to being diagnosed. I was put on insulin injections right away. It wasn't until recently that I had a C-peptide test to discover that I'm actually a Type 2, however I produce such low amounts of insulin myself, my endo felt that staying with insulin was the best treatment. He thinks that my 10 or so years prior to starting treatment, and then my on/off relationship with treatments through the years pretty much killed any chance I might have to being off insulin completely.