By manapua72 Latest Reply 2012-12-19 14:04:17 -0600
Started 2012-12-17 00:11:03 -0600

I just was reading a report on metformin and how they thought it might help to prevent cancer … That's a good thing … Doctors said it lowered the amount of insulin in the blood … They said high levels of insulin lead to higher levels of certain cancers … Just what I needed to hear … I hope this isn't really so … Had any one heard of insulin causing cancer ??? I gotta do more research …

29 replies

MrsCDogg 2012-12-18 06:38:37 -0600 Report

I had those side effects from metformin. As long as the dose was relatively low like 250mg I was ok. As soon as my doc started to "tweek" my dose by raising it I started to get sick from it. All the problems were gastrointestinal which made me really miserable. So I had to stop taking it and go to something else. I now take Actos, Januvia, and Lantus. I know a lot of people say that insulin does not cause weight gain but I think it does. In my opinon (which doesn't really count for much) ALL diabetes drugs cause weight gain. I have also been on byetta which caused the same effects as metformin. I've heard that byetta can help you to loose weight. If it helps with weight loss it's because the food doesn't stay in the body long enough to cause ANY weight gain!

manapua72 2012-12-17 20:50:34 -0600 Report

I never had any problems with Metformin … It's just that I have a hard time remembering to take pills … Anyways I was on it for 10 years just got taken off of it … I knew it had certain side effects I just didn't realize so many people suffered from that …

jayabee52 2012-12-18 00:30:19 -0600 Report

it seems to be a sizable minority who have that problem. but maybe it seems like it because those who have no problem with it don't complain about it (I had no digestive problems wth it when I was on it either). And I have read in other discussions where ppl had troubles with it at first but got used to it. Everybody's different!

Krystabela 2012-12-17 20:09:33 -0600 Report

I've been on Metformin and absolutely am not fond of it at all. It had some horrible side effects that made living life away from the house difficult…at least for me. Also I was on Metformin for awhile when I was diagnosed with Endometrial Cancer a year ago. Now the cancer is gone but I'm on Megace which did help with my form of cancer, but as a negative it also increases appetite. As to insulin causing cancer…never heard of it.

jigsaw 2012-12-17 08:41:19 -0600 Report

Well, I read about newly discovered complications that are related to diabetes quite frequently. If you listen to all the possibilities, it almost seems like it is impossible to stay alive with diabetes. Quite frankly, I do the best I can to take care of myself, and minimize my stress caused by my concerns related to diabetes. Stressing, will certainly make matters worse. I have had diabetes for many years, and yet I have not experienced any complications. If and when I do, that's when I'll deal with it. For now, I remain focused on taking care and enjoying !

frog1951 2012-12-17 13:21:20 -0600 Report

I tried metformin and it caused direrra - I had to go every 30 mins or so. That would not work. Yes it would lower my readings because everything I took in was flushed. I can't live like that. CURE not treatment

Krystabela 2012-12-17 20:11:41 -0600 Report

same issue here. As I'm dependent on riding a bus I had to time everything by how long it would take to get to my stop or simply not leave the house. It was a horrible way to live

jayabee52 2012-12-17 14:05:29 -0600 Report

unfortunately it seems like cure is a long way from becoming reality. The best we can hope for right now is getting on the right treatment.

jigsaw 2012-12-17 14:04:14 -0600 Report

Fortunately, for those of us that need medications, there are various choices. Not all meds work for all people. If you are having uncomfotable side effects with one medication, why not try another ?

frog1951 2012-12-17 14:11:30 -0600 Report

What happens when you have tried all of them and still can't find an answer. I have been a type 2 for 30+ years and it has progressed until I can't get it under control regardless of what I do. There has to be a cure or I will be dead soon. It is sad that doctors won't listen as I had told them a lot that has been ignored. They only hear the first sentence then ignore the rest.

jigsaw 2012-12-17 14:25:52 -0600 Report

Have you ever been on long term insulin and or short term insulin ? That would be a last alternative prescribed by doctors, when oral meds no longer work. I know that doctors hesitate to prescribe insulin only to type 2s that are still producing some insulin. This is because of the chance of experiencing dangerous lows amongst other risks. I realize that you may be aware of this, but I thought I would ask.

frog1951 2012-12-17 15:00:04 -0600 Report

I am currently on Lantus and U500 insulin - I still run in the 200's and sometime dip to 50 or below. My pancreas still works some of the time causing it to be very difficult to control my BS

Caroltoo 2012-12-17 14:20:58 -0600 Report

Would you consider reevaluating some approaches that are less medical and more lifestyle change?

jigsaw 2012-12-17 14:33:34 -0600 Report

Caroltoo, I believe all with diabetes should consider lifestyle changes that can often lead to natural approach and success with managing diabetes.

frog1951 2012-12-17 15:05:08 -0600 Report

I have been the natural way and heavy exercise -did not work for me. I have made lifestyle changes and diet changes - if they would find a cure it would involve you metabolism also. This is a multi-facet disease. Unfortunately doctors are single threaded - when you go to the doctor they only allow one thing per visit. I wish my treatment was a simple as some suggest but I am highly resistant and always have been. I was normal weight when diagnosed. The treatment has cause me to gain weight even with the same exercise and diet considerations. Too many people judge others based on their experience - if they were not very bad, they tend to minimize the treatment. It is not that easy for some people.

Caroltoo 2012-12-17 20:18:49 -0600 Report

Yes, this is a multifaceted and very complex disease and I didn't find my first doc very helpful either, which is why I started trying things on my own. Sorry that you haven't found yet what will really work for you. It's taken me about 10 years with some good and poor results to move from BG of 400 to normal, but I feel really blessed that it has happened, though it was anything but simple to do.

jigsaw 2012-12-17 16:38:28 -0600 Report

If you are absolutely 100% positive that your understanding and perceptions are 100% accurate, then I will say a prayer for you.

phoenix20 2012-12-17 23:34:26 -0600 Report

My sister is on long term insulin and short term insulin also. Her blood sugar is real high most of the time but she doesn't take care of herself and diet. She just eats what she wants. She has all kinds of medical problems also. I worry about her but she doesn't do anything.

jigsaw 2012-12-18 07:30:28 -0600 Report

It's a sad situation, when someone does not take care of themselves, especially with diabetes. If she is in denial, then all you can do is try different approaches to reach her. Sometimes, and unfortunately it can take some hard circumstances to break through denial.

frog1951 2012-12-17 20:23:06 -0600 Report

I have been on insulin since 1990 - I was diagnosed in 1983 - prayers are always accepted, thanks. I have been frustrated with the lack of anything in the direction of a cure -they really don't know exactly what causes type 2 - all the research is on type 1 which is only 5% of the total. That leaves 95% out in the cold. If it is too difficult then the blame game comes in. I am sick of the medical profession saying - you didn't do this, you did this. I am not a computer and do not respond like a computer - I can't and will not eat the same thing every day. But they still blame me. I did not ask for this disease but I have seen very little done - just someone saying they are researching - not results driven. I was an engineer until I was force out of the workforce due to cognizant problems - probably caused by diabetes or Agent Orange.

jigsaw 2012-12-19 08:13:46 -0600 Report

In all due respect, I have had some different and some similar experiences when it comes to diabetes. I do not see a right or a wrong. There have been numerous times when I thought there was no better answer when my diabetes became more difficult to manage. I never gave up hope, and always continued to look, search and learn. So far, I have always managed to find a somewhat positive and satisfying answer, and end up managing my diabetes with success. In part, I believe the reason for my success is that I refuse to believe that I am doomed. Should I ever get to the point where I believe the opposite, then that would become my unfortunate reality, and I would have no reson to search for answers.

frog1951 2012-12-19 14:04:17 -0600 Report

I was diagnosed type 2 in 1982 - I have went through so many treatments that did not work, it is difficult to keep a positive outlook. I wish I could but at the present, they cannot find anything that works. Unfortunately I have chronic back problems - multiple surgeries - I have watched trillions of dollars flushed down the drain because most of the doctors and researchers do not listen to people like me. They like to blame instead of finding answers. There has been nothing significant done in over 10 years - maybe they are spending time trying to find a cure, but I don't see that.

jayabee52 2012-12-17 01:23:29 -0600 Report

I believe that that was news on DC a couple weeks ago. search for "metformin and cancer" I did and got 101 responses from that query. Happy hunting!

manapua72 2012-12-17 06:22:33 -0600 Report

James I was just taken off of metformin … I've heard how it may help against cancer which is a good thing … What the article was saying was that it lowered the amount of insulin in your body … Went on to say that some doctors felt that high levels of insulin lead to higher levels of certain cancers … I'm on insulin …

frog1951 2012-12-17 14:08:58 -0600 Report

There are a lot of us that cannot tolerate metformin. It give me massive diarrhea. I was on it for two months and ended up in the hospital because the doctors insisted it would go away. It did not. Cure not treatment!!!!!!!

jayabee52 2012-12-17 14:21:00 -0600 Report

That is a common complaint for Met, but a lot of people started out on that med without much trouble (me included)

Unfortunately it seems like CURE is a long way from becoming reality. The best we can hope for right now is getting on the right treatment FOR YOU.

Ive done the oral meds route and the injected insulin route and now I am able to do it without diabetes medication of any kind just by following a low carb high protein meal plan. That works for me.

I'd certaily like to be cured as I am sure most everybody else would too, but reality interferes and we must go on and do what is needed to manage our diabetes. Any amount of wishing, hoping or ranting will not change that.

Rant if you need to, but it woun't change the course of finding a cure for diabetes.

frog1951 2012-12-17 14:54:11 -0600 Report

The squeaky wheel gets to oil. The more times it is said that researchers are not looking in the right direction will get results. I am also another good example. I volunteered for many studies at Kirklin Clinic in Birmingham, Al. The only people they took had to be able to go to the hospital during the day for 3 hours. That eliminated stressed out daytime workers (me). It is sad that most research is misguided and misinformed. They always go in the wrong direction and thus avoid a cure.

Caroltoo 2012-12-17 00:22:36 -0600 Report

Yes, I've heard it described as one of the complications of diabetes. Makes it one very good reason to take good care of ourselves!

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