Common diabetes drug could fight ovarian cancer

By GabbyPA Latest Reply 2012-12-08 16:10:14 -0600
Started 2012-12-08 16:10:14 -0600

Who Knew?? What an interesting article. I just thought you guys would like to know.


By Loren Grush, Published December 03, 2012

The commonly prescribed diabetes drug metformin could potentially double as an effective form of ovarian cancer treatment, according to a new study.

Researchers from the Mayo Clinic found that ovarian cancer patients – who also had diabetes – lived longer than other ovarian cancer patients when they were taking metformin. According to the scientists, they had been researching the link between metformin and its potential anti-cancer properties for many years.

“We had a pretty good idea that metformin has anti-cancer activity, because a lot of people around the world have been reporting the link between metformin intake and a protective effect against cancer for a number of years now,” Dr. Sanjeev Kumar, a Mayo Clinic gynecologic oncology fellow, told “[Viji Shridhar, one of the study’s co-authors,] has been conducting a lot of experiments in her lab and has published extensively in the area, so we had a lot of cell data, mice data – and then we decided to test our hypothesis in humans.”

Kumar and his colleagues examined 239 ovarian cancer patients, 61 of whom were taking metformin. Compared with the other 178 patients, those taking metformin had a much higher survival rate – with 67 percent of the metformin-taking patients surviving after five years, versus 47 percent of those who were not taking the medication.

When taking into consideration other factors – such as the patients’ body mass indexes or the severity of their cancer – those who were taking metformin were four times more likely to survive than those who did not take the medication.

Read more:

No replies