I just ran across some hopeful news for T1’s. Independent research is being done by Dr. Denise Faustman at Faustman Lab where it is claimed that T1 diabetes had been successfully reversed in mice back in 2001, and now this is being taken into human clinical trials.
Her theory is that our beta cells are simply suppressed by a less than optimally functioning immune system, and if those poorly functioning factors in the immune system are taken out and transplanted with healthy, then maybe normal blood sugars would result. From my limited understanding, transplant isn’t the issue, rejection is, and her work is looking into “introducing the concept of modifying antigens on donor tissues to prevent their rejection.” Sounds a lot to me like the “sleeping islet” theory.
Visit the site here for more info http://www.faustmanlab.org/ It appears she has an association with Massachusetts General Hospital and Harvard Medical School, but they are asking for funding help (I am not attempting to solicit funding, that’s your choice.)
Clinical human trials are a big deal with this type of research. It means they’ve cleared the multiple hurdles that few have ever cleared before. It is expected to be a 4 phase, 8-10 year trial. Phase 1 trials started in 2008, and phase 2 in 2011. If you so choose, you can enroll and be screened to participate in phase 2 of these trials.
I’d be interested if anyone here would consider participating.
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