Look at this....

By TsalagiLenape Latest Reply 2012-08-12 13:51:25 -0500
Started 2012-08-08 18:34:22 -0500

Came across this today…thought it had merit to check over. What is your opinion?


29 replies

Nick1962 2012-08-09 08:54:37 -0500 Report

Excellent! This, along with possible Islet Transplant Therapy means there might just be a cure possible, or at least some relief. Folks can tell me diabetes is incurable, but I'll continue to say "why not"?

Diefleu 2012-08-10 01:32:31 -0500 Report

I don't mean to be negative but sometimes I wonder if they don't cure diabetes because its just to much of a money maker.

Nick1962 2012-08-10 07:41:45 -0500 Report

Oh no doubt there is money to be made off us. But if you look at the number of diabetics in the US, it's really a small percentage, and with so many other illnesses and diseases cropping up (HIV, obesity, etc.), iff diabetes were fully cured, there really wouldn't be any significant losses to the various industries. Just my 2 cents.
Honestly though, many diabetics (and I'll probably get some flack for this) are diabetics of choice. I know it can be controlled (in T2's) without medication for many. I myself am off medication and have been told by my PCP I no longer need to test, so I'm technically "off the payroll". There are many who could easily do what i did but choose not to, and the med/pharma communities will make their money off those folks just like the sugar industry makes money off soda drinkers and the tobacco industry makes money off smokers. For some diabetes is more of an addiction than a disease.

jayabee52 2012-08-10 14:08:44 -0500 Report

You'll get no flack from me on what you said, Nick.

I also am kinda "off the payroll" too, the only thing I pay out for is Dr visits and meter strips. Now if I could reverse my declining Kidney function numbers and avoid dialysis, I'd be "golden". (My numbers just recently took a drop :-( and may be on dialysis in about 1 month, or even sooner)

jayabee52 2012-08-10 15:22:07 -0500 Report

I am trying to put off the dialysis for as long as possible through lifestyle choices, but I think I am going great having put it off for about 2 yrs now. (that means no more meals or custards from Culvers for me).

jayabee52 2012-08-10 02:14:55 -0500 Report

that has been on the minds of a LOT of PWDs over the years.

Yet think of the money that someone who finds a cure could make selling the "cure". I am sure it would be in the Billions.

Diefleu 2012-08-10 02:36:57 -0500 Report

Name another disease that has been cured. Not vaccinated but straight up… They cured a disease… The fact is that between meds, test strips, glucometers, needles, ect they are making a fortune. Its like residual income and in all the years the big break through… You can test your arm instead of your finger… We can send rovers to mars… But hey you can now prick your arm instead of your finger.hmmmm something seems slightly off balance to me

jayabee52 2012-08-10 03:08:49 -0500 Report

you are not alone in those feelings. I myself sometimes have feelings like that, but then I get over it and get on with my life and confrol my diabetes.

What is more they're not getting all that rich on me as I don't need diabetes meds. I do use meter strips but haven't bought a meter in years.

Also in response to your "rant" above, how do we force a medical breakthrough? How do we "demand more" —- and actually get it?

Diefleu 2012-08-10 03:17:06 -0500 Report

Well thats the real question… Imo… We stop getting excited about the meters they come out with that really don't do anything different. Or the "convient" pen style insulin delivery system that really broken down is not that impressive and we gather up, write to ada and other charities that are raising so much money. I'm really obviously not sure I just know that in some way we should be doing better.

JSJB 2012-08-10 04:09:06 -0500 Report

Hey rant all you want that is what keeps us going. I beleive in what you say about getting a cure. Look at MS. All those telethons and the amount of mone raised but no cure just some releif. Now if there was a cure Jerry would be out of work:) I'm pre diagnosed about 10 months ago and since joining DC read many articles about getting a cure but right now we can only control it by exercise, diet and meds.

jayabee52 2012-08-09 13:01:35 -0500 Report

Wouldn't Islet Transplant Therapy necessitate the use of antirejection medication? I remember reading the article and it stated: "According to the U.S. Centers for Disease Control and Prevention, the only groups that shouldn't receive the live vaccine are those whose immune systems are compromised, such as people who have HIV or people who have received an organ transplant."

I wanted to make sure I wasn't talking through my hat on that so I googled "Islet Transplant Therapy" and found this: "Rejection is the biggest problem with any transplant. The immune system is programmed to destroy bacteria, viruses, and tissue it recognizes as "foreign," including transplanted islets. In addition, the autoimmune response that destroyed transplant recipients' own islets in the first place can recur and attack the transplanted islets. Immunosuppressive drugs are needed to keep the transplanted islets functioning." (complete article may be found here ~ http://diabetes.niddk.nih.gov/dm/pubs/pancrea... )

So until a way is found to not weaken the immune system yet keep the Islets of Langerhans working, this TB vaccine would be contraindicated.

(sorry to be a wet blanket)

I pray it could be done someday, somehow!

Nick1962 2012-08-09 13:58:38 -0500 Report

Yes, i had considered that, but had also considered the question in the article …"Would such regeneration take place in humans with type 1 diabetes if the immune-system attack that causes type 1 diabetes in the first place was stopped?" If that immune system that is responsible for rejection, even temporarily, can be lessened to allow the good T cells to outnumber the bad, then i saw that as selective rejection. I'm no scientist, but the concept seems promising. There has been speculation that islets don't die, they just go dormant, and can be woken up. This article seems to support that theory somewhat IMHO.

MAYS 2012-08-09 13:17:54 -0500 Report

James, you are correct!
Weakening of the immune system and rejection are two of the biggest drawbacks, eventually the antirejection medications become ineffective and the body will begin attacking both itself and the transplanted organs and cells.