pre-diabetes or metobolic syndrome

By highlandcitygirl Latest Reply 2009-03-06 21:42:02 -0600
Started 2008-11-15 21:24:29 -0600

i went to the doctor this past week. he had told me before that i had pre-diabetes,now he is calling it metobolic syndrome,can anyone tell me has the labeling been changed? my home testing ,which i didn't tell him about,. is steadily climbing

5 replies

2008-11-17 15:53:59 -0600 Report

Pre-diabetes and Metablic syndrome are two different things although related. Pre-diabetes is a term used when your fasting blood sugars are between 110 and 125, this means 'it's coming, if you don't do something now'. Actual Diabetes is diagnosed when two consecutive fasting tests are 126 or higher. Metabolic syndrome is a combination of conditions including diabetes, high blood pressure and high cholesterol. If you google both of these terms I'm sure you'll find a lot of information.

Metabolic Syndrome

What is the metabolic syndrome?

The metabolic syndrome is characterized by a group of metabolic risk factors in one person. They include:

* Abdominal obesity (excessive fat tissue in and around the abdomen)
* Atherogenic dyslipidemia (blood fat disorders — high triglycerides, low HDL cholesterol and high LDL cholesterol — that foster plaque buildups in artery walls)
* Elevated blood pressure
* Insulin resistance or glucose intolerance (the body can’t properly use insulin or blood sugar)
* Prothrombotic state (e.g., high fibrinogen or plasminogen activator inhibitor–1 in the blood)
* Proinflammatory state (e.g., elevated C-reactive protein in the blood)

People with the metabolic syndrome are at increased risk of coronary heart disease and other diseases related to plaque buildups in artery walls (e.g., stroke and peripheral vascular disease) and type 2 diabetes. The metabolic syndrome has become increasingly common in the United States. It’s estimated that over 50 million Americans have it.

The dominant underlying risk factors for this syndrome appear to be abdominal obesity and insulin resistance. Insulin resistance is a generalized metabolic disorder, in which the body can’t use insulin efficiently. This is why the metabolic syndrome is also called the insulin resistance syndrome.

Other conditions associated with the syndrome include physical inactivity, aging, hormonal imbalance and genetic predisposition.

Some people are genetically predisposed to insulin resistance. Acquired factors, such as excess body fat and physical inactivity, can elicit insulin resistance and the metabolic syndrome in these people. Most people with insulin resistance have abdominal obesity. The biologic mechanisms at the molecular level between insulin resistance and metabolic risk factors aren’t fully understood and appear to be complex.

The American Diabetes website has a good explanation of Pre Diabetes.

highlandcitygirl 2008-11-19 20:10:04 -0600 Report

thank you so much for this information. i see myself in everything that is written here. i don't have pre-diabetes,i have diabetes.

highlandcitygirl 2008-12-29 20:01:46 -0600 Report

i wonder how many peaple have this"pre-diabetic" condition.

diabetesdoctor 2009-03-06 21:42:02 -0600 Report

Based upon my experience, a lot of people have pre-diabetes but they don't know it.

Pre-diabetes and the onset of Type 2 diabetes can be completely PREVENTED — if people (and doctors) understood the set of blood tests required for a proper diagnosis, e.g. blood pressure, HbA1c, lipid profile, insulin resistance (IR), CRP, homocysteine, etc. Measuring the fasting blood glucose can "hide" the disease for months if not years.

FYI: A simple way to diagnose insulin resistance and hyperinsulinemia is a fasting serum insulin and a c-peptide level. In the pancreas, when insulin is made, it starts out as two fragments attached to each other by a connecting peptide called c-peptide. When this molecule comes out of the pancreas, two pieces split off the c-peptide, to form regular insulin, and the insulin and c-peptide exist separately. For each molecule of insulin made, a molecule of c-peptide is made, so that high insulin secretion by the pancreas is associated with high c peptide levels. If fasting serum insulin is high (greater than 20), or if c-peptide is high (greater than 4.6), then it is very likely that insulin resistance syndrome is present. This can occur with normal blood glucose or commonly in type 2 diabetes, with high blood glucose, can lead to the insulin resistance syndrome.

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