By DavinaRN Latest Reply 2016-04-15 10:23:56 -0500
Started 2012-04-15 20:28:55 -0500

Wondering if anyone else is on this? Just took my first dose Friday evening (loving the once a week shot, but it did hurt more). I "feel" so much better but not sure if it is this (was on byetta before) or the 50,000 IU of vitamin D that I started at same time.

37 replies

Bobbiev 2016-04-15 10:23:56 -0500 Report

I started Bydureon about a month ago. My sugars are wonderful, and I've been able to cut down on my insulin dosages to prevent low blood sugar reactions, but I'm getting terrible stomach aches that feel like acid reflux (which I already have and take medication for). Sometimes I feel nauseous, too, but haven't vomited so far. I want to stick with this drug because of the excellent blood sugars, but it's going to be hard if I'm going to get belly aches like this most of the day. Can any of my fellow Bydureon users reassure me? Thanks in advance and love, Bobbiev

DJ Bakier
DJ Bakier 2016-03-11 21:39:58 -0600 Report

I was prescribed Bydureon a couple of weeks ago. My doctor said I was only the second person he has prescribed it to, so he wanted me to come back in a month to give him a report. I took my first dose last Tuesday at 5 p.m. I had a decent size meal at 8 pm. At around midnight I began violently vomitting, pretty much every 10 minutes for 5-6 hours. It was so bad I couldn't breathe at times from the wretching. I could barely move from the nausea for the rest of the next day. I had to take the next day off from work. I don't want to scare anyone else about this drug, but I don't think I can go through that again. Has anyone else had an experience like this?

kathy5701 2015-11-17 21:42:22 -0600 Report

I posted last year how wonderful this product is but I have been on it for about 1 1/2 years. My appetite came back and I gained the 20 pounds I lost. But in October we came back from a trip to Hawaii and I was the highest weight I have been in years. So I was determined to lose. I quit the sugar and bread and pasta. I try to move more. It's been 5 weeks and I have lost 13 pounds. I am determined to get it together.

xchellelynnx 2015-05-06 10:13:52 -0500 Report

Thank you everyone for your comments. I just started this drug and have been quite concerned with my numbers. I was taking Victoza and metformin only and was never over 200 after meals and usually fasting was 100 or lower. With this new medication even 3-4 hours after meals I am still 160-200 and it's scary compared to what I normally had on Victoza. At least I know I am not the only one.

kathy5701 2014-07-07 11:31:28 -0500 Report

I have been on Bydureon for almost 9 weeks. It is like a miracle if you can handle the nausea. I have lost about 10 - 12 pounds which I needed to do. It has helped me stick to low carb, no sugar, no breads and smaller meals. I find that I do better on 4 to 5 small meals a day. Like someone else posted I could never stop myself from eating too much even if i was miserable afterwards but with this medication your reach your full level and you have to drop the fork immediately. I cannot explain the feeling. My husband and I went to a BBQ at some friends and there was like 15 people and I don't know what I ate but I went outside for fresh air and threw up in some bushes all my dinner and my 1/2 glass of wine too. Anyways my Fasting and 2 hour after eating Blood Sugar numbers are Awesome!!. Morning fasting last time was 103. My 2 hour numbers have never been above 140. I am also on High Blood Pressurea and High Cholesterol Medication. I take 6 prescriptions plus this weekly injection. I am really hoping to get off some of these meds.

@wisewoman 2015-11-17 09:25:29 -0600 Report


I have been on Bydureon for 8 months and have lost 42 pounds plus, i live in the UK and dont understand the sugar readings posted on this site. The tummy thing does settle down x :)

NE Dave
NE Dave 2012-05-24 15:21:26 -0500 Report

I'm on my second week, I've switched from Byetta.

I had seen the warnings about blood sugar going up at first, and boy that's turned out to be true. On Byetta I was averaging 140 fasting, sometimes just over 200 post-meal. So far on Bydureon, fasting is all over the place — sometimes 120, sometimes 200. Post-meal has been downright scary, ranging from 200 to 400. I've tried to cut carbs dramatically and that's helped, and gradually I'm having fewer terrible readings and more so-so readings (not many "good" readings).

Given experiences reported here I won't give up yet. The once/week would be a big help as I travel frequently, and I've seen the data showing better long-term control vs Byetta. Still, I have not had a number above 300 since I was first diagnosed 10 years ago, so seeing all those "3"s has been really disturbing. :(

Zero gastro-intestinal side effects. I had mild nausea my first month on Byetta back in 2008, but fine since and no issues since changing to Bydureon.

J7daniels 2012-08-30 15:19:58 -0500 Report

I'm on my second week too and I too travel a lot - this week I hit 421 and I am almost always over 200! Totally agree the highs are a concern. I too have zero side effects while Byetta upset my stomach. I really hope this stuff kicks in soon.

DavinaRN 2012-05-27 22:21:27 -0500 Report

my levels have finally reached normal, although I have just had my first low, but still only one in seven weeks.

NE Dave
NE Dave 2012-05-31 11:17:48 -0500 Report

I'm willing to give it another month, but at the end of 3 weeks I'm still running 150-180 fasting, and consistently 250 for several hours after meals. And that's making a real effort to eat better than I was on Byetta, e.g., today I had an apple and a slice of ham for breakfast and was still at 250. On Byetta I was 120-150, and very rarely >200 after meals. At least I haven't seen any more in the 300s, but pretty discouraging — really hope it improves.

veebs 2012-05-16 12:41:07 -0500 Report

Yup. Just switched from Byetta to Bydureon. Once-weekly part is great but doing the injection is an annoying little ritual. Glucose levels are coming down, but gastro side effects are a bummer. Don't know which end to stick in the toilet first …

DavinaRN 2012-05-17 21:17:09 -0500 Report

I found it really helps to limit how much I eat. If I only eat 1-2 cups volume wise I do a lot better.

Lizardfan 2012-04-16 22:04:56 -0500 Report

Great endo visit today! A1C decreased 1.6 which really made my day. I also lost 17lbs since my last visit. I am doing Weight Watchers and had already lost about 6lbs before beginning Bydureon.

DavinaRN 2012-04-17 19:58:48 -0500 Report

That's great. I lost 8lbs when I started byetta again in feb but then hit a plateau. Hoping I start dropping again with bydureon

Lizardfan 2012-04-17 22:04:50 -0500 Report

Hopefully you will start losing again. The Bydureon gives you a different type of appetite suppression, sort of you are full even before you start to eat. Plus, for me I get the start of nausea feelings if I over eat a tiny bit. I stop eating immediately when that happens.

murmouse 2012-04-16 12:31:22 -0500 Report

My blood sugar got really high on it in the beginning (which my doctor failed to warn me about). One of these discussions actually alerted me to the fact it can take a full 6 weeks to get in your system. BS has gone back down (I take my 7th shot tomorrow) but not as low as it had been on Victoza and I did have to up my dosage of Glimepiride. Weeks 2-4 were really bad for me because I experienced extreme dizziness. It has disappeared so I'm hoping I'm done with that side effect. Other than that, no other side effects which was great because Byetta made me violently ill when I was on it. Have my first checkup on Friday since starting the Bydureon so I will post my results as well.

veebs 2012-05-16 12:42:35 -0500 Report

Same here. I was up in the 200s and 300s for a couple of weeks, even when I avoided carbs completely. Now the Glucose levels are still falling after 6 weeks. Tired of puking though …

DavinaRN 2012-04-16 21:49:16 -0500 Report

My sugars actually hit normal the next day and suddenly I felt great. Not sure if it was bydureon or the fact I started vit D 50,000 IU at same time.. So far I've had no side effects other than decreased appetite but I had that with byetta also. Just glad this one doesn't make me neausated. I go back in 3 months for check up. Hoping my HgA1c drops some although technically it is good at 5.4

murmouse 2012-04-26 12:14:18 -0500 Report

I'm curious how you are doing with the Bydureon. I switched back to Victoza at the end of my 8th week. My A1c went up .4 and no weight loss so the dr gave me a choice of staying with it or switching back. My Bydureon numbers never got as good as the ones I had on Victoza.

DavinaRN 2012-04-30 21:02:12 -0500 Report

I take my 4th shot Wednesday and my fastings are70's-low 80's, post meal around 120. I don't go back to Endo until July for recheck, but my A1c started at 5.4. As to weight I hanging out at same weight, but have PCOS that I'm trying to get back under control which doesn't help with weight.

NurseKeri55 2012-07-23 09:34:23 -0500 Report

I have PCOS too and just took my first Bydureon injection. I ws on Byetta 10 for 5 years. I have insulin resistance but have never been diagnosed with diabetes (hope never to). I have been so frustrated with the weight issue. I am now on the IP diet and it is working so I hope to lose the frustrating weight that I have been unable to lose. I too am an RN. Hope no side effects from this as it is so much simpler to do once a week!

murmouse 2012-04-30 21:22:58 -0500 Report

It was my endo's opinion that the PCOS was inhibiting my weight loss too. I lost about 65 lbs pre-diabetes diagnosis but had to cut out all carbs to do it. I cant do that with the medications i am taking and once i started taking meds i plateaued big time. I guess as long as the numbers arent going up i shouldnt complain, but it would be nice to lose those last few pounds. Good luck!

DavinaRN 2012-05-02 19:27:40 -0500 Report

Tell me about, I took myself off my yasmine last year (lesson learned) and ended up with two 10lb weight jumps. I've lost one of them, but can't seem to lose the other. Upping my workout time.

Lizardfan 2012-04-16 12:13:45 -0500 Report

I have been on Bydureon since mid February and I love it! You may get higher BS readings for several weeks before they settle down. So far I am the only patient taking it on DC that I know of. I will be happy to answer and questions you may have. There is a FB group called Byetta and Diabetes that has a lot of patients on it, you have to join to post but you can read all you want. That helps me a lot. Since it is so new there is not a lot of real time information out there. I have used the BydureonSteadySupport site too. Let us know how you are doing. I am on my way to the endo today for my first check up since starting so I will let you know how I am doing. Good luck!

robinrn 2012-05-11 00:39:44 -0500 Report

Just had my second injection and have found that this stuff really hurts! Almost feels like a tetnus shot. Any ideas?

DavinaRN 2012-04-16 21:52:43 -0500 Report

Just picked up my next four weeks supply, wanted to make sure I didn't have a problem with it first. So far I love it, no side effects, sugars normal next day and I feel great. Although not sure if it was bydureon or starting 50,000 IU of vit D

Caroltoo 2012-04-15 20:45:39 -0500 Report

Can't speak to Bydureon, but I'm curious: how often are you taking the 50,000 IU of vitamin D and for what period of time?

DavinaRN 2012-04-15 22:06:17 -0500 Report

Once a week for 10 weeks is what Gyn prescribed, but endocrinologist said she will change it if my level really was the 3.1 they told me.

Caroltoo 2012-04-15 23:59:57 -0500 Report

Thanks. I take 4,000/day, but had seen another person mention taking the 50,000 and was curious about it. Why don't you search "Bydureon"? I believe there is another discussion currently about it and at least two others have acknowledged using it.

Caroltoo 2012-04-16 22:01:33 -0500 Report
This one is by lizardfan.

To do a search, go to the discussion page like you did to start your discussion. Then immediately below where you clicked on the blue box that says "Start a New Discussion" is another smaller blue box which says "Search". Enter the contents of the search in the blank box to the left and click on the Search box.

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