Bydureon

Lizardfan
By Lizardfan Latest Reply 2016-02-23 23:41:30 -0600
Started 2012-02-15 21:41:10 -0600

I started Bydureon today! I have been on Byetta for six years, my A1C was starting upwards due to progression of diabetes. My endo @ Joslin suggested I give Bydureon a chance.

I had researched the medication and was happy to try it. I had my training on how to mix the medication and inject, it was so easy. So far no side effects and my pre dinner BS level was 99 and PP was 89. I did a 5 mile walk which accounts for some of that I am sure.

Any one else taking Bydureon? It is so brand new I am hoping to connect with others trying it as well. Thanks in advance.


37 replies

@wisewoman
@wisewoman 2015-11-17 09:29:59 -0600 Report

I have been on Bydureon for 8 months I live in the uk so its hard to follow the progress of others. I feel really well !!!

@wisewoman
@wisewoman 2015-11-05 07:41:16 -0600 Report

I have been taking Bydureon since March 2015, weight loss 3 stone plus. So much more mobile and energetic. I am still taking insulin but reduced from 158 twice a day to 25 twice a day. I would like to develop a support group to exchange stories please.

AZjenny
AZjenny 2015-02-17 16:33:48 -0600 Report

I just took my first Bydureon injection last night. I had no issues with the mixing process. Only took a few minutes. The injection also was no issue. I thought I was doing well until earlier today. Woke up with a terrible headache that even with taking something has still lingered in the background all day. Also the nausea. It's not debilitating but it is hindering my desire to eat. I've managed to nibble on some pretzels and one container of yogurt but that's about it. Anyone have any issues with this? Any idea on how long it could last? Is it normal for the side effects to start about 10 hrs after the first injection?

TIA

bigtmt
bigtmt 2015-02-15 17:08:47 -0600 Report

i just took my 2nd injection of Bydureon and have immediately sick to my stomach after the dose. I have Crohns also so I don't know if this has anything to do with it or not. I never had a problem as such while taking Lantus.

Rachel K.
Rachel K. 2014-07-23 09:34:54 -0500 Report

Hi! My name is Rachel Knobloch and I work at a marketing research firm in the Atlanta area. We have been hired out to find those who are current Bydureon users for an interview regarding the medication and it's management of type 2 diabetes. We are interested in opinions only and no solicitation will result upon completion of the interview, your anonymity would be protected. They would like to chat for an hour over the phone and compensation for taking the time out of your schedule to share your thoughts would be $75. They are also looking for a current user to come in to participate in a face to face interview in the Atlanta area at our offices and will offer $100 for referrals who participate in the session seeing there are such a limited number in the United States taking this medication. If you are interested and would like further information please feel free to contact me directly at 770-394-8700 X 205, email me at rknobloch@jacksonassociates.com small or check out our website at www.jacksonassociates.com. If you would like to share this with anyone else you know it would be greatly appreciated!

Anonymous
Anonymous 2014-07-15 12:19:33 -0500 Report

I have been taking it for about 10 weeks now.
Morning bs levels are not great, but they do go down during the day.
The injection site nodules are terrible, big, hard and painful.
I am not sure if these are side effects of bydureon, but this all seems to be happening at the same time: bad acid reflux, bad taste in mouth, hotter and sweating more than usual, bad abdominal bloating, loss of hair .
I was on byetta for a few years, had many of these same symptoms but no where near the severity. I have an appointment with Endo nurse Friday; Wednesday is injection day and I will not be taking it. I need to figure out what is causing all these issues. I am not sure if Metformin is playing a role in there as well.

Go texans44
Go texans44 2015-06-10 10:50:32 -0500 Report

Nodules could be because bydureon is not at all close to our natural endogenous glp1 we have in our body. It is made from lizards spit. Look it up. More antibodies as well. It's a dog drug. I don't understand why anyone would take this with other options on the market. Good luck

Wingnut49
Wingnut49 2016-02-23 23:41:30 -0600 Report

Insurance has changed me over to Bydureon. I've been on Byetta for about 13-14 years. I have not taken my first dose because I still have three months of Byetta left. "Exenatide is a synthetic version of exendin-4, a hormone found in the saliva of the Gila monster that was first isolated by John Eng MD in 1992 while working at the Veterans Administration Medical Center in the Bronx, New York." Does not bother me at all because many medications are made from plant or animal research.

Barbneilon
Barbneilon 2014-07-07 12:02:03 -0500 Report

I've been on Bydureon for about 10 months. It seems to be keeping my A1c at a reasonable place. I've switched the days I take it several times — forgetfulness or delays in delivery. In January when we switched mail order pharmacies my insurance didn't want to pay for it, so it took an intervention from my doc to get an approval for 1 year. I suppose we'll have to do that all over next Jan.

I don't have any side effects from it other than the lumps & some itching at the site for a day or 2 after especially when I inject in my thigh. It's not so noticeable in the abdomen. I've never had nausea nor been told to take it near a meal.

My weight has remained a bit lower than when I started it, but I'm not so impressed with this promise.

Anyone have trouble with the mixing?

Barb

kathy5701
kathy5701 2014-05-22 21:17:06 -0500 Report

I also started Bydureon last week. My plan was to do thursday nights at about 4PM and then eat dinner. I forgot tonight to take it so now I am thinking I will do tomorrow morning before breakfast. Any thoughts about getting sick if taking the injection too soon after eating? My doctor said to take 1 hour before a meal. Thanks

murmouse
murmouse 2012-04-26 12:17:08 -0500 Report

I swirtched back to the Victoza yesterday. My a1c had increased .4 and no weight loss. My bs numbers never got quite back to where they were on Victoza. How's your progress?

cooperrod
cooperrod 2012-04-14 17:40:10 -0500 Report

Hello, today I started on Bydureon. I have been on Victoza for 3 months and lost 10 lbs. I had nausea every day, it was horrible. Any updates from the Bydureon users?

kathy5701
kathy5701 2014-06-11 13:09:00 -0500 Report

I have been on Bydureon for over 4 weeks. Initially I felt a little tired and nausea after the injections but now I really don't notice anything. I am getting much better numbers on my finger poking. Used to be 225 - 275 and now average is about 150. I am hoping my A1c is down in August at my next dr visit. I am getting the Lumps where I inject. The very first one has never gone away yet. As far as weight loss I can't say it has affected me regarding that. I wish it would. :-)

Lizardfan
Lizardfan 2012-03-27 14:53:54 -0500 Report

Update! Continuing to do well on the medication. I am having very good blood sugar control, I see the endo in three weeks and can't wait to see what my A1C is going to be! I have found one injection nodule, very small and getting smaller, and no other side effects to report. All in all, a good decision on my part to try this med.

Lori in Arvada
Lori in Arvada 2012-03-28 01:38:41 -0500 Report

I did good on it too. Lost 15 pounds in three weeks. However, just found out today that they undercharged me for my first month's dosage. What they charged me for the entire month is what they were supposed to charge me for ONE shot. My insurance company doesn't cover it, so I guess I'll never find out how it would have worked, since I can't afford it.

murmouse
murmouse 2012-03-19 13:04:49 -0500 Report

My endo switched me from Victoza to Bydureon. I am doing my 4th shot tomorrow. So far I am not having great results. I switched to Victoza from Byetta because my nausea was so severe I couldn't eat/sleep/function. My BS was better on Byetta but not where I felt it should be. The Victoza, however, was great. I was able to cut back on some of my oral meds and my numbers were consistantly below 110. My fasting glucose numbers which had always been an issue were under 100. Since starting the Bydureon my BS has shot up. I am near 200 almost always 2 hours post meal. My blood sugar goes up and stays up regardless of the carb/protein content of what i eat or any exercise I do. My endo says I have to give it time to "kick in" but in the meantime I am having extreme dizzy spells and trouble focusing even when my BS is relatively low (which is now the 140-160 range). On the upside…no nausea. I'm curious (since there don't seem to be many discussions out there by people taking Bydureon) if anyone can offer me any suggestions. Is it worth it to stay on it if I feel so bad and my numbers are WAY out of range? How long would you wait before switching back to a medication you know you were successful on? I am taking 1500 mg Metformin and also 1 mg Glimepiride (which I was able to discontiue on the Victoza). It's disappointing and frustrating to see the numbers climb after I worked so hard to get them down.

Kerry Johnson
Kerry Johnson 2014-06-09 22:25:07 -0500 Report

I have been researching this medication because after my fourth dose last week I had to be rushed by ambulance to the er. I have had nausea, dizziness, weakness, to the point I couldn't do my job. The er doc said I was having the side effects that were serious and should no longer take the medicine. So he put me on zoo ran for the nausea and said it should be out of my system in a few days. I have also gained 8 pounds. I hope this helps you.

mkhojh99
mkhojh99 2012-04-26 12:47:30 -0500 Report

I have done a lot of readin and most say it takes 6 to 7 weeks for this medicine to take full effect.

cooperrod
cooperrod 2012-04-14 17:42:03 -0500 Report

Any updates on your numbers?

murmouse
murmouse 2012-04-14 18:11:42 -0500 Report

6 weeks in and my fasting is down in the low 100s. Post-meal BS has also improved greatly. Weight loss was not the primary reason I took this and I haven't weighed since I started the Bydureon. My endo appt is next Friday so I will update with weight loss (if any) and changes in A1c. I like the convenience of the once a week shot but think I may switch back to Victoza. It seemed to work better for me.

Lizardfan
Lizardfan 2012-03-19 15:42:23 -0500 Report

I was told when I started Bydureon that it could take up to six weeks for it to fully kick in. Have you spoken to your doc about this? I am also on the facebook group Byetta and Diabetes and there are several patients on Bydureon there as well. Some of them are having higher blood sugars and are concerned about it too. Call the Bydureon helpline, the number is on the box, and see what support you can get there as well. I have found them very helpful. I take my 6th injection this week and I am very happy with it. I had a brief bout of nausea yesterday just out of the blue. Not too unpleasant but that has happened a few other times as well. I am losing weight slowly, but I am on WW and trying, and my sugars have stabilized for the most part and averages are 114, 115,119 for the last three weeks. Good luck, hoping you can find the right thing for you to do.

Lizardfan
Lizardfan 2012-03-14 13:19:56 -0500 Report

Week 5 shot today and still going strong. I am having some out of range readings, most of them are below 110. Seems like the bedtime readings are when I get the spikes. Some of them I am left scratching my head wondering what went wrong? LOL! Still no problems mixing or injecting. I have it down to a science and it takes no time at all to do the procedure. Two brief bouts of nausea so far, and only one low blood sugar. I was almost done with a 4 mile walk and got that *low* feeling. When testing I was in the lower 60's. I am symptomatic below 70. I had a no sugar added fruit cup,my after exercise snack anyway and in 10 minutes was in the low 80's. I love, love the convenience of once a week shot. Had some issues getting my script filled MO, but other than that enjoying the whole experience. Good luck to everyone in our quest for healthy living.

martin54
martin54 2012-02-25 17:43:13 -0600 Report

That is great news and yes but she has not got a chance to review it yet so I will stay on the byetta for know until I see her again in a couple of months . The byetta is working lost almost 40 pounds and a1c went from 11.2 to 7.8 .
Sounds like it is working for you good luck and keep the updates coming I think you ate the only one on this site taking it,

martin54
martin54 2012-02-17 18:36:29 -0600 Report

Thanks for the info Byetta also made me nauseous at first to but you learn what to eat and what not to. I have lost weight with it which is a plus before Byetta my sugars where in the 300's now in the 90's most of the time so it does work.

Well see my endo this week and will ask about I like having to do it only once a week.

Thanks again and keep posting the info is great!

Lizardfan
Lizardfan 2012-02-25 17:18:08 -0600 Report

Did you speak with your endo regarding the Bydureon? I would love to hear your experiences. I am finding no place to discuss with other Bydureon patients. There is a UK website but I have had no response.

martin54
martin54 2012-02-16 19:58:07 -0600 Report

You are the first person that I know had used it I have been on Byetta for 3 months and it works well for me just an upset stomach if I eat to much but I would love to go from 2 injections a day to one a week please let us know how it works for you I see my endo next week and I am going to ask about Bydureon

PPNCHER69
PPNCHER69 2012-09-19 20:00:37 -0500 Report

YOU SHOULD NOT BE GETTING UN UPSET TUMMY FROM THE BYETTAA IF YOU EAT TO MUCH, I HAVE BEEN ON BYETTA FOR 3 YEARS NOW, FOR ME THE SIDE EFFECT WAS WEIGHT LOSS, I LOST 75 LBS IN 6 MONTHS, BUT THAT SUBSIDED HOWEVER IT HAS KEPT MY SUGAR IN CHECK.AND AS FAR AS THE NAUSIA SIDE EFFECT, THAT HAPPENED ONE TIME AFTER BEING ON IT FOR 2 YRS AND LASTED ABOUT 2 MINUTES RIGHT AFTER I TOOK IT, IT WAS WEIRD. TODAY IS MY FIRST BYDUREON INJECTION, WERE TRYING TO BOOST MORE WEIGHTLOSS.

martin54
martin54 2012-09-20 00:16:19 -0500 Report

Well every one has different side effects and I know a lot of people who if they over eat get nausea that is why you get the weight loss I have been on it for 10 months and have lost 90 pounds and lowered my A1c from 12.4 to 6.2

Lizardfan
Lizardfan 2012-02-17 16:16:19 -0600 Report

Hi Martin! Thank you for your interest. I am the first patient in my Joslin group to start on it. I called on the day the FDA approved it and said to please sign me up! The group had their drug rep launch on the 7th and the DE called me back to answer some of my questions about it. A week later she called telling me that it was in the pharmacy pipe lines now and I could pick up a script if I wanted to. I took the script to WalMart and they ran it thru the system to see if my insurance would cover it. They of course did at the 80/20 usual rate. I did have to return again to the center to have her show me how to mix and inject the medication.

I had researched and watched the video on Bydureonbyyourside.co.uk so I knew what to expect. She had an empty kit, when she started the presentation I asked her if I could do it for her to make sure I had it right! I did it flawlessly and then I injected the actual meds. It was so easy!

The mixing is easy, and no I had never done that before either! The needles are the same length as Byetta, they are just thicker. I had to look to make sure it was in as I didn't feel it at all. I counted to ten, and one thing I will tell you it bled just a bit, so have a tissue or bit of gauze when you inject.

It made an even smaller bruise mark than Byetta, and I got no bump as is reported that can happen. Yesterday I had a smaller than small egg sort of countour area, not welt, hard to explain, like the medication had spread out to a bigger area. This is how the medication gets into your blood stream. No redness, itchiness, etc.

Will continue next post.

Lizardfan
Lizardfan 2012-02-17 16:24:01 -0600 Report

Last night I felt just a twinge of what might be the start of a headache, but it went away and did not develop. Plus a bit of nausea that never developed. Mind you, when starting Byetta in 2006 I had a LOT of nausea so I have been extremely careful with what I have been eating. The minute I get a signal that I am full I stop right then. So far it has been wonderful.

The highest BS reading has been 111 this morning, I was only 77 at bedtime last night and since it is a new med I didn't want to go low so I may have had too many carbs as a bedtime snack. My last two days bedtime readings have been 79 and 77. That is a little low for me.

I am also on Metformin 2500 a day and I am one of those people who do go low. I can't wait to see how my A1C responds.

Please ask any questions that you want. I am happy to help, so many people helped me when I first started Byetta years ago, I am just paying it forward. Plus I am hoping others come forward to teach me something too!

There is a website BydureonSteadySupport(SM) that has a video that is excellent. It shows the presentation of the mixing and injecting and then an actual person does it. Very helpful!

jayabee52
jayabee52 2012-02-15 22:51:55 -0600 Report

Howdy "Liz"

That is wonderful. No I don't take it, (or any other diabetes med only meal plan and exercise controls mine).

Please keep us updated on how it goes with you on this new med.

Praying it will be a positive for your diabetes control!

James Baker

Lizardfan
Lizardfan 2012-02-16 13:41:34 -0600 Report

Thank you for your kindness James! Having a great day too. Fasting was 104 this morning and pre lunch was 99, so it is working for me. Seems so odd not to be injecting the Byetta! I am also taking Metformin too.

I was diet and exercise controlled for two years when first diagnosed, I loved the no meds! Congrats that you can take care of yours by D&E. Alas, the old diabetes progression gets me from time to time.

PPNCHER69
PPNCHER69 2012-09-19 20:04:50 -0500 Report

YOU MENTION THE LOW NUMBERS, FOR ME I FEEL GOOD IF MY BS IS AT 120-140, IF ITS 100, 90, 04 79 I GET SCARED TO DEATH AND FEEL JUST HORRIBLE, MY DOCTOR SAYS ITS CAUSE MY BODY ISNT USED TO BEING AT A NORMAL NUMBER, HOW LOW CAN I GO WITHOUT PASSING OUT,
I DIDNT KNOW THAT LOW SUGAR IS POSSIBLE WITH THIS, HAD I KNOWN I DONT THINK I WOULD HAVE SWITCHED OFF OF THE BYETTA. THATS TERRIFIES ME ESPECIALLY IF IM ALONE WHEN IT HAPPENS. ANY IDEAS?

jayabee52
jayabee52 2012-02-16 14:11:26 -0600 Report

My diabetes did not seem to progress that much or that fast over the 16 + yrs with it. I started out on Met (of course!) and when my kidneys quit working I was changed to insulin. Initially NPH insulin 10 U AM and 7 U PM. I ended up taking 15 U AM and 12 U PM before I embarked on my med free "experement".

When I read of folks on insulin injecting what I thought were astronomical amounts of insulin, I thought I was really on a "baby dose" of NPH, a longer acting insulin. Thought why not try to do what I had wanted to do. My carbs are radicallly lowered but once I got used to it I love it.

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