Type 1 Heredity?

RebC
By RebC Latest Reply 2011-11-07 08:01:43 -0600
Started 2011-11-03 17:21:00 -0500

Does anyone know what the likelihood of passing on type 1 diabetes is? I have read in places that it is considered non-hereditary, due to it being an auto-immune disorder, but recently my endocrinologist told me that since I have two auto-immune disorders (diabetes and thyroid issues), my children have a 25% chance of getting it as well. So now I'm paranoid. I have a two year old and one on the way…I don't want them to have to deal with this!


13 replies

annesmith
annesmith 2011-11-06 22:43:22 -0600 Report

HI AGAIN…I'm sorry…I have a fever and I am a little bit disoriented. I reread your situation, and in my strong opinion, they probably will not get diabetes. 25% is only one fourth a chance. If they get it, my strong opinion is they would get type 2 diabetes, not type 1…again, I could be wrong, but, children get type 2 also…or, they might get it later on in their adulthood——ANNE

annesmith
annesmith 2011-11-06 22:40:04 -0600 Report

I have known some people in families where the father had type 1, then 1 or 2 of his kids got it. I am not a doctor, but my own opinion of autoimmune is that it all depends on if the children have a lower resistance to a major flu or cold. I think type 1 is genetic and also caused by a huge destruction of beta cells…why they get destroyed nobody knows. I had a HUGE fever/flu, and cold when I was 8 years old, and I have never been the same since. However, I was flagged in my birth hospital record as a strong possibility of being diabetic when I as born. In my case, the genetics were already there without a doubt——both my parents are/were diabetic, plus every single female on one side of my family had type 2, with my great grandmother they think was probably type 1 insulin dependent. I honestly think it's genetic predisposition, then a huge virus attacks, or something related. However, some kids are born insulin dependent immediately…that I am not sure at all as to why it happens…that sounds genetic to me, too…ANNE

Type1Lou
Type1Lou 2011-11-05 16:59:36 -0500 Report

Here are links to an ezine article and an ADA article that you might find helpful and reassuring: http://ezinearticles.com/?How-is-Diabetes-Inh... and
http://www.diabetes.org/diabetes-basics/genet...
It's not as clearcut as your doctor led you to believe.
I just googled "inheriting diabetes" and came across these two articles…I'm sure there's more out there…don't you just love this information age! Mays actually cited this ADA article in a discussion a year ago…search the DC discussions for "genetics and diabetes" . I'm sending you a paragraph from the ADA article that may tie in more closely to what your doctor was saying…
Hugs,
Lou

RebC
RebC 2011-11-06 19:06:27 -0600 Report

Thanks for the info…interesting stuff. I guess I am just paranoid. I don't want to be the mom who pokes her kids fingers every time they get a little bit hyperactive, but let's face it…I probably am that mom. LOL

dietcherry
dietcherry 2011-11-04 20:25:46 -0500 Report

Hello! I remember reading some time ago that the chances of a T1 Father passing it to his offspring are higher (25%) than a T1 Mother doing so, but I cant recall the percentage of her passing it :(

Type1Lou
Type1Lou 2011-11-05 08:45:17 -0500 Report

Interesting…I suspect that my Dad actually had Type 2 because he was 62 when it was diagnosed…but I don't think oral meds had been available to him back then. In any case, this is reassuring info for RebC.

dietcherry
dietcherry 2011-11-05 11:29:13 -0500 Report

Now I wish I would have posted that info here at DC as soon as I read it :( Neither of my parents have T1 or T2; as far back as both can recall, no family members had T1 and only 2 had T2 (Dads side) so the odds of actually getting it are anyones guess

Type1Lou
Type1Lou 2011-11-04 18:40:55 -0500 Report

Type 1 diabetics, statiscally make up only about 10% of the diabetes population. My Dad developed diabetes when he was in his early 60's in the mid-1950's. I'm not sure whether he would have been classified as a Type 1 or Type 2 but I think the only treatment back then was for him to take insulin. I know of no other family members with diabetes (besides me). Thyroid disease seems to be very prevalent in us diabetics. I have it too. While I think there is a genetic component, I don't think they really know what triggers the auto-immune response that destroys our insulin-producing beta cells. Do your offspring have a higher chance of developing diabetes?…perhaps but I wouldn't let the doctor's injudicious comment rattle me…I like James' approach that even if the 25% chance is accurate (and I'm not certain it is), that still means they have a 75% chance of not getting it. When are you due?

RebC
RebC 2011-11-06 19:02:08 -0600 Report

I'm due in April. :)

Type1Lou
Type1Lou 2011-11-07 08:01:43 -0600 Report

My cousin's daughter is also due with her second child in April. She is the closest thing to a daughter I will ever have since I never gave birth. It's not so far away, is it? Hope all is going well for you and baby and family.

jimmyjames43
jimmyjames43 2011-11-04 14:42:05 -0500 Report

i have been passed eery issue my mother had so far,Diabetes,and heart disease, but we also lived similar life styles,do the best you can with a healthy life and eating style,that would be my advice,and take it from there,no one really knows what our gene pool is going to hand us