Is there a way to prolong the honeymoon phase for type 1 diabetes.

By thajek Latest Reply 2015-08-05 14:19:01 -0500
Started 2011-08-10 12:55:19 -0500

My 3 year old daughter was recently (6 weeks ago) diagnosed with type 1 diabetes. After the initial hospital stay, IV fluids and training for my wife and I about how to check BG levels and give insulin shots we have had to constantly adjust dosages down. So many lows, then highs, sleepless nights etc..

We were told initially about the honeymoon phase where her pancreas has recovered a little after initial treatment and is still producing insulin, be in insufficient amounts and seemingly somewhat sporadically.

One of the first things that came to my mind was that I, as a parent, need to try and stop whatever is happening that is killing my daughters beta cells to preserve as much function as possible. However, it seems that most of the doctors that we talk to are just interested in the usual treatment plan.

I read of a clinical trial that was done using Interferon alpha (I think this is an auto-immune suppressant which is used for HIV/AIDS, Hepatitis B and C) to prolong the honeymoon phase.

Does anyone have any thoughts on prolonging this honeymoon phase? How long did yours last? I've read it's typically about 4 months to 2 years? Is there any hope for this?

I don't want to drag my daughter through test after test or blood draw after blood draw, it's hard enough to get the finger pokes and injections but I also don't want to find out in a year or two or five that if I had done X,Y, or Z then I might have been able to stop to total destruction of my daughters insulin producing cells.


2 replies

kyeremin4 2015-08-05 14:19:01 -0500 Report


My 4 year old son was diagnosed with type 1 diabetes 2 1/2 weeks ago. I am curious as to how your child is doing right now and how the honeymoon phase went. Hope things are going well!

kdroberts 2011-08-10 21:08:34 -0500 Report

4 months to 2 years is very unrealistic, that's closer to what the participants in clinical trials are achieving. Most people find that it lasts a few days, maybe a few weeks, often though you never even notice. Even if you prolong it or it lasts longer or even during any stage of it, it doesn't mean that the pancreas is working 100% normally, just that the beta cells aren't 100% knocked out. Somebody with 20% beta cell functionality would still be on the honeymoon phase but they would still need insulin. The only way to affect it and make it last longer is to do a clinical trial, and that won't guarantee anything and it won't stop destruction long term.

The questions you have to ask yourself are what are you trying to do? and what options do you have and what will they do? You will almost certainly find that what you want to do is very different to the reality of what can be done even if you have the option of doing it. Unfortunately it's an autoimmune attack with no current way of stopping it, the trials you mention are right now are only really trying to slow it down.

I'll also add that the honeymoon phase isn't always a good thing. Because the natural production of insulin is often unpredictable you can end up with some quite severe lows as well as very high highs because you never really know how much insulin your body is going to produce.