Diabities and Morphine.

By jeffie_3 Latest Reply 2018-03-02 01:08:12 -0600
Started 2011-05-08 22:16:40 -0500

A few years ago a Dr. put me on morphine, for pain management. It had one great side affect. It controlled my ups and downs. I lost weight, I became much more active. In the process, it seems I needed less and less diabetes medication.
When this Dr. left the practice I was removed from the morphine. With in two months I found myself on insulin. My a1c went from 5.7 to 7.8. For over a year and a half, I have had trouble controlling my blood best a1c was 6.8. I then had an injury and was given a supply of morphine for one and a half months. My blood sugar levels went down to 75 to 130 steady. I had to stop the insulin because of the lows and my a1c was 5.8 . I am now out of the morphine and I am staying in the 175 to 225 range and I am back on the insulin. Any thoughts? Anyone have any information on this?

12 replies

PosX 2018-03-02 01:08:12 -0600 Report

I’ve been on chronic pain meds since 2010 under a pain management Dr. for 2 failed spinal fusions, lot of nerve damage, was then told early 2017 that I was Pre-Diabetic. I’ve been on Nucynta ER and IR, then changed to Opana/Oxymorphone ER/IR. Each twice a day. None of those have affected my blood sugar, then this year 2018, my company changed prescription plans and denied my Oxymorphone ER because I haven’t tried Morphine Sulfate. So on 2/14/18 I was put on it, also twice a day, 7am and 7pm, about a week later I’ve become very weak feeling and sleeping a lot more then usual. My blood sugar had been lowering slightly, but figured was because lack of eating since I was sleeping more. Then on 2/27/18 my daughter had a school band concert that evening, my blood sugar that day had been 130 to 180. We ate a burger and fries before leaving, I also took my pills, the Morphine Sulfate. During her concert, I became extremely weak and couldn’t keep my eyes open. We left as soon as she was done, I tested as soon as we got home and it was 72! I ate a Swiss cake roll and tested an hour later, it read 169. On the 28th, I slept most of the day and only tested once, after supper at 5:30pm it was 194. At 7pm I took my round of pills and then slept. Morning of March 1st, blood sugar was 76. Through out the day after eating, test were all around 190. Before supper at 5:43 it was 210. Had small portion of steak, about a table spoon and a half of mashed potatoes and corn, I also took my pills afterwards. At 7:44pm it read 242. Exactly 2 hours later before bed, 9:44 pm it read 81. My next appointment with Pain Management is 3/14/18, I’m going to see if I can be put back on the Oxymorphone ER, now that I tried the Morphine Sulfate, so hopefully Insurance will cover it now since the Morphine Sulfate is taking my life away from my family. I’m just worried what all the Morphine will do to me before my appointment date.

john sanders
john sanders 2017-01-13 11:54:01 -0600 Report

They don't tell you but morphine and cocaine were the standard treatment for diabetics in the late 19th and early 20th century. You can fine articles about its use in old Medical journals if you look on line. Unfortunately diabetes is not a recognized use for opiates. According to the old studies All opiates will lower your blood sugar levels but morphine is the most potent. Many could control their type 2 diabetes with morphine alone.
The real danger is to type 2 diabetics but can effect type i also and that is if you are using insulin and a doctor prescribes an opiate for pain you can go into a coma very quickly if you continue at your regular dosage. You will need to watch that very closely as it happened to me. Unfortunately most doctors don't know this. I was severely injured and ended up on morphine for 5 years. initially the orthopedist who prescribed the morphine did not know of this interaction and I passed out from low blood sugar but those with me realized what was happening and gave me a large number of my tablets. It was only after this that I began to question and research this as even my specialist did not realize that it could be that acute an action. I went from using 1200 to 1500 units a day to less than 300 units while on morphine. Finally had surgery that worked and off morphine now for 8 months. Back to 1200 units of insulin daily. Hope this helps. Use with care

OsloNorway 2018-02-28 17:11:05 -0600 Report

Could You please supply an article or book reference about what You vrote here since this is exactly
What I experienced when I had dental work done and afterwards was
Given pro Morfin drugs as painkillers
Suddenly I was of minimum need of insulin injections.
And as You vrote
I was not warned about it

MCPJr 2017-05-19 11:35:57 -0500 Report

My neurologist is intrigued by this subject as I was on morphine for a very long time and my glucose was controlled. I titrated off of it recently to try another medication and my glucose rose dramatically. I would greatly appreciate it if you could forward me links of your search into morphine being the "drug of choice" in the beginning of diabetes treatment. My searches seem to get waylaid, so if I could get a starting point it would help greatly!
Thanks, Mike

dietcherry 2011-05-09 20:43:58 -0500 Report

I had it once; I seizured in the shower last September and cracked a rib on the tubs edge on the way down. I was screaming in the ER when the Dr. touched me so they gave me morphine to shut me up! lol As Jim said, it was delightful! But not enough experience with it to determine effects on my numbers.

jeffie_3 2011-05-09 20:26:36 -0500 Report

To Amourer.. I will try to find a study I ready about diabetics and how it take two to three times the dose, to be affective for a diabetic. I know when I take it, it doesn't make me feel like I'm taking it. It does dull the pain. But not like I expected. Also if you have a heart attack and your diabetic, You need to inform the Dr. that morphine is somewhat ineffective in relaxing your heart. I thank all of you for sharing with me.

Harlen 2011-05-09 14:51:55 -0500 Report

It makes you eat less too I was on it for 4 months but that was 23 years ago
How's the pain ????
Best wishes

Armourer 2011-05-09 10:52:56 -0500 Report

1.5 years ago I was in the hospital for a week due to blacking out from low blood pressure. At this time I had severe sciatica and was given morphine for the pain. I don't know about the BG numbers but the morphine they gave me was overrated. Didn't give me a moment of relief! They sure were tight fisted!

moldybacon 2016-10-22 16:52:46 -0500 Report

I had severe nerve pain for years. My Dr. put me on Morphine, and other pain killers for break through pain, and they didn't touch it. Finally I went to a Dr. who gave me gabapentin which is for seizures, but also helps with nerve root pain. It was my saving grace I probably wouldn't still be here without it. I know the threads old but just incase someone stumbles upon it I thought I'd put my two cents in.

Jim Edwards
Jim Edwards 2011-05-09 11:04:20 -0500 Report

I have had morphine once it my life; it was delightful! I had extreme pain in my lower back, regardless of the position I was in. Went to the ER and was admitted. They started an intervenous drip line and they strapped me it. I protested, "What if I need to get up and use the bathroom" You push the button and you will use the bedpan". Jim was not a happy camper. About 30 minutes later she came back in and asked how I was doing. "Fine" I replied sharply. She told me to hold out my hand and rub my fingers together. I could feel nothing! I put my one hand to the other and "washed my hands" Nothing!
"That is why you are strapped in. You would not be able to feel the floor under your feet and you would fall". Ok, I replied sheepishly.

jeffie_3 2011-05-09 06:35:20 -0500 Report

Thank you jaybee52. I have been doing allot of reading on the subject. I am stuck going to a certain group of Dr. and the new head Dr. feels I'm full of it. I have been googleing the subject and found allot of information. I found a few on dopamine and on cortisol levels. Raising dopamine and lowering cortisol. There is also a new type 2 drug that does just that, raises dopamine levels..As for pain levels. I have had my left leg crushed twice, and it is 2-1/2 inchs shorter than the other. Along with several other broken bones. Also suffer from pitformis syndrome. Those are just my major pain problems.

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